Gene Symbol | STX4 |
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Entrez Gene | 6810 |
Alt Symbol | STX4A, p35-2 |
Species | Human |
Gene Type | protein-coding |
Description | syntaxin 4 |
Other Description | renal carcinoma antigen NY-REN-31|syntaxin 4A (placental)|syntaxin-4 |
Swissprots | Q6FHE8 A8MXY0 Q15525 Q12846 |
Accessions | EAW52175 EAW52176 EAW52177 Q12846 AF026007 AAB88810 AF318489 AAG40313 AJ000541 CAA04174 AK091833 BAG52424 AK296652 BAH12411 AK315716 BAG38075 BC002436 AAH02436 BI755734 BQ775670 BT007326 AAP35990 CR541806 CAG46605 U07158 AAA20967 X85784 CAA59769 XM_005255521 XP_005255578 XM_011545925 XP_011544227 NM_001272095 NP_001259024 NM_001272096 NP_001259025 NM_004604 NP_004595 |
Function | Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in neutrophils and neutrophil- differentiated HL-60 cells. Expression in neutrophils increases with differentiation. {ECO:0000269|PubMed:10080545}. |
Top Pathways | Vasopressin-regulated water reabsorption, SNARE interactions in vesicular transport |
Human Syntaxin 4 full length protein - ab132537 from Abcam
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Human Syntaxin 4 protein fragment - ab114464 from Abcam
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Human Syntaxin 4 protein fragment - ab131680 from Abcam
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STX4 / Syntaxin 4 Antibody Blocking Peptide - LS-E6181 from LifeSpan Bioscience
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STX4 / Syntaxin 4 Antibody Blocking Peptide - LS-E21782 from LifeSpan Bioscience
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STX4 / Syntaxin 4 Antibody Blocking Peptide - LS-E21783 from LifeSpan Bioscience
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Syntaxin 4 Recombinant Protein - H00006810-P01 from Novus Biologicals
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Syntaxin 4 Partial Recombinant Protein - H00006810-Q01 from Novus Biologicals
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Recombinant Human Syntaxin 4 Protein - NBP2-22843 from Novus Biologicals
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STX4-Antibody-Center-Blocking-Peptide - BP18817c from Abgent, a WuXi AppTec company
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Recombinant Human Syntaxin 4, CF - 7894-ST-050 from R&D Systems
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Human STX4 protein - orb169369 from Biorbyt
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KLRB1 protein (His tag) - 80R-2422 from Fitzgerald
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STX4 Blocking Peptide - 33R-9505 from Fitzgerald
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STX4 Blocking Peptide - 33R-5072 from Fitzgerald
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STX4 protein (His tag) - 80R-2411 from Fitzgerald
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Syntaxin 4 / STX4 (1-275, His-tag) - AR50491PU-N from Acris Antibodies
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Syntaxin 4 / STX4 (1-275, His-tag) - AR50491PU-S from Acris Antibodies
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Syntaxin 4 / STX4 - H00006810-P01-10 from Acris Antibodies
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Syntaxin 4 / STX4 - H00006810-P01-25 from Acris Antibodies
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Syntaxin 4 / STX4 - H00006810-Q01-10 from Acris Antibodies
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Syntaxin 4 / STX4 - H00006810-Q01-25 from Acris Antibodies
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STX4, 1-275aa, Human, His tag, E.coli - 01-P1667 from ARP American Research Products
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STX4 fusion protein - Ag7053 from Proteintech Group
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STX4 fusion protein - Ag6973 from Proteintech Group
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