Gene Symbol | STX4 |
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Entrez Gene | 6810 |
Alt Symbol | STX4A, p35-2 |
Species | Human |
Gene Type | protein-coding |
Description | syntaxin 4 |
Other Description | renal carcinoma antigen NY-REN-31|syntaxin 4A (placental)|syntaxin-4 |
Swissprots | Q6FHE8 A8MXY0 Q15525 Q12846 |
Accessions | EAW52175 EAW52176 EAW52177 Q12846 AF026007 AAB88810 AF318489 AAG40313 AJ000541 CAA04174 AK091833 BAG52424 AK296652 BAH12411 AK315716 BAG38075 BC002436 AAH02436 BI755734 BQ775670 BT007326 AAP35990 CR541806 CAG46605 U07158 AAA20967 X85784 CAA59769 XM_005255521 XP_005255578 XM_011545925 XP_011544227 NM_001272095 NP_001259024 NM_001272096 NP_001259025 NM_004604 NP_004595 |
Function | Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in neutrophils and neutrophil- differentiated HL-60 cells. Expression in neutrophils increases with differentiation. {ECO:0000269|PubMed:10080545}. |
Top Pathways | Vasopressin-regulated water reabsorption, SNARE interactions in vesicular transport |
Syntaxin 4 (H-16) - sc-14455 from Santa Cruz Biotechnology
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Syntaxin 4 (E-18) - sc-14454 from Santa Cruz Biotechnology
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Syntaxin 4 (QQ-17) - sc-101301 from Santa Cruz Biotechnology
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Anti-Syntaxin 4 antibody - ab77037 from Abcam
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Anti-Syntaxin 4 antibody - ab57841 from Abcam
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Anti-Syntaxin 4 antibody - ab101879 from Abcam
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Anti-Syntaxin 4 antibody - ab138744 from Abcam
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Anti-Syntaxin 4 antibody [EPR15472] - ab185556 from Abcam
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Anti-Syntaxin 4 antibody [EPR15473] - ab184545 from Abcam
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Anti-STX4 / Syntaxin 4 Antibody (aa131-160, APC) - LS-C270624 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa131-160, AP) - LS-C270625 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa131-160, FITC) - LS-C270626 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa131-160, Biotin) - LS-C270627 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa131-160, Azide-free, HRP) - LS-C270629 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa131-160, PE) - LS-C270631 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa131-160) - LS-C325479 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa1-50) - LS-C290977 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa19-120, Azide-free) - LS-C328824 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (C-Terminus) - LS-C135543 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa92-297) - LS-C186377 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa1-297) IHC-plus™ - LS-B9936 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa101-150) - LS-C135544 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (aa131-160) - LS-C157108 from LifeSpan Bioscience
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Anti-STX4 / Syntaxin 4 Antibody (clone 6A1) - LS-C139164 from LifeSpan Bioscience
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Syntaxin 4 Antibody (884637) [Unconjugated] - MAB7894 from Novus Biologicals
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