HEYL

Gene Symbol	HEYL
Entrez Gene	26508
Alt Symbol	HESR3, HEY3, HRT3, bHLHb33
Species	Human
Gene Type	protein-coding
Description	hes-related family bHLH transcription factor with YRPW motif-like
Other Description	HEY-like protein\|HRT-3\|class B basic helix-loop-helix protein 33\|hHRT3\|hHeyL\|hairy-related transcription factor 3\|hairy/enhancer-of-split related with YRPW motif 3\|hairy/enhancer-of-split related with YRPW motif-like protein
Swissprots	Q5TG99 Q9NQ87
Accessions	EAX07260 Q9NQ87 AF311885 AAG31158 AJ272215 CAB75716 AK300463 BAG62182 AL541019 BC006087 AAH06087 BM682076 EU446871 ABZ92400 XM_005270745 XP_005270802 NM_014571 NP_055386
Function	Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. {ECO:0000250, ECO:0000269\|PubMed:15485867}.
Subcellular Location	Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00380, ECO:0000255\|PROSITE-ProRule:PRU00981}.

HRT3 (N-19) - sc-16448 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

HRT3 (N-19): sc-16448. Western blot analysis of HRT3 expression in C3H/10T1/2 whole cell lysate.

HRT3 (C-18) - sc-16449 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

HRT3 (3555C3a) - sc-81294 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

HRT3 (3555C3a): sc-81294 Western Blot analysis of human recombinant HRT3 fusion protein.

Anti-Hey L antibody - ab61277 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-Hey L antibody [3555C3a] - ab54359 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3555C3a

Anti-Hey L antibody [3555C3a] (ab54359) + immunised recombinant protein

Anti-HEYL Antibody (aa34-47) - LS-C24222 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody - LS-C125696 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-HEYL Antibody - LS-C67863 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal

Anti-HEYL Antibody (aa26-54, AP) - LS-C258436 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody (aa26-54, APC) - LS-C258437 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody (clone 3555C3a) - LS-C184526 from LifeSpan Bioscience

Prices	$335.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	3555C3a

Anti-HEYL Antibody (aa26-54, Biotin) - LS-C258438 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody (aa26-54, FITC) - LS-C258439 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody (aa26-54, Azide-free, HRP) - LS-C258440 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody (aa26-54, PE) - LS-C258441 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody (aa25-54) - LS-C321935 from LifeSpan Bioscience

Prices	$435.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody (N-Terminus) - LS-C30789 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-HEYL Antibody (clone 3555C3a) - LS-C342563 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3555C3a

Western blot analysis of immunized recombinant protein, using anti-HEYL monoclonal antibody.

Anti-HEYL Antibody (aa26-54) - LS-C166849 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Fluorescent confocal image of HeLa cell stained with HEYL Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with HEYL primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). HEYL immunoreactivity is localized to Mitochondria significantly.

Anti-HEYL Antibody (clone 1F6) - LS-C133717 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1F6

Immunoperoxidase of monoclonal antibody to HEYL on formalin-fixed paraffin-embedded human colon. [antibody concentration 1.5 ug/ml]

Hey L Antibody (1F6) - H00026508-M07 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1F6

Hey L Antibody (4A11) - H00026508-M02 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4A11

Hey L Antibody - NBP1-89981 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: Hey L Antibody [NBP1-89981] - Staining of human bone marrow shows strong nuclear positivity in bone marrow poietic cells.

Hey L Antibody - NBP2-16817 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: Hey L Antibody [NBP2-16817] - A: Hep G2.

Hey L Antibody (2B4) - H00026508-M11 from Novus Biologicals

Prices	$349.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2B4

ELISA: Hey L Antibody (2B4) [H00026508-M11] - Detection limit for recombinant GST tagged HEYL is approximately 10ng/ml as a capture antibody.

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