Gene Symbol | HEYL |
---|---|
Entrez Gene | 26508 |
Alt Symbol | HESR3, HEY3, HRT3, bHLHb33 |
Species | Human |
Gene Type | protein-coding |
Description | hes-related family bHLH transcription factor with YRPW motif-like |
Other Description | HEY-like protein|HRT-3|class B basic helix-loop-helix protein 33|hHRT3|hHeyL|hairy-related transcription factor 3|hairy/enhancer-of-split related with YRPW motif 3|hairy/enhancer-of-split related with YRPW motif-like protein |
Swissprots | Q5TG99 Q9NQ87 |
Accessions | EAX07260 Q9NQ87 AF311885 AAG31158 AJ272215 CAB75716 AK300463 BAG62182 AL541019 BC006087 AAH06087 BM682076 EU446871 ABZ92400 XM_005270745 XP_005270802 NM_014571 NP_055386 |
Function | Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. {ECO:0000250, ECO:0000269|PubMed:15485867}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}. |
HRT3 CRISPR/Cas9 KO Plasmid (h) - sc-406928 from Santa Cruz Biotechnology
|
||||||||
HRT3 HDR Plasmid (h) - sc-406928-HDR from Santa Cruz Biotechnology
|
||||||||
HRT3 Double Nickase Plasmid (h) - sc-406928-NIC from Santa Cruz Biotechnology
|
||||||||
HRT3 Double Nickase Plasmid (h2) - sc-406928-NIC-2 from Santa Cruz Biotechnology
|
||||||||
HRT3 CRISPR Activation Plasmid (h) - sc-406928-ACT from Santa Cruz Biotechnology
|
||||||||
HRT3 CRISPR Activation Plasmid (h2) - sc-406928-ACT-2 from Santa Cruz Biotechnology
|
||||||||
HRT3 Lentiviral Activation Particles (h) - sc-406928-LAC from Santa Cruz Biotechnology
|
||||||||
HRT3 Lentiviral Activation Particles (h2) - sc-406928-LAC-2 from Santa Cruz Biotechnology
|
||||||||
HRT3 siRNA (h) - sc-37918 from Santa Cruz Biotechnology
|
||||||||
HRT3 shRNA Plasmid (h) - sc-37918-SH from Santa Cruz Biotechnology
|
||||||||
HRT3 shRNA (h) Lentiviral Particles - sc-37918-V from Santa Cruz Biotechnology
|
||||||||
Hey L RNAi - H00026508-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU044601 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN10007 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10007 from Sigma-Aldrich
|
||||||||
HEYL siRNA (Human) - CRH8838 from Cohesion Biosciences
|
||||||||
HEYL - MBS8201596 from MyBioSource
|
||||||||
shRNA set against Human HEYL (NM_014571.3) - SHH311849 from Creative biogene
|
||||||||
shRNA set against Human HEYL(NM_014571.3) - SHH119405 from Creative biogene
|
||||||||
Human HEYL siRNA - orb269340 from Biorbyt
|
||||||||
HEYL shRNA Plasmid (Human) - CHH8838 from Cohesion Biosciences
|
||||||||
HEYL miRNA 3'UTR clone - MiUTR1H-04475 from Creative biogene
|