Gene Symbol | ADIRF |
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Entrez Gene | 10974 |
Alt Symbol | AFRO, APM2, C10orf116, apM-2 |
Species | Human |
Gene Type | protein-coding |
Description | adipogenesis regulatory factor |
Other Description | adipogenesis factor rich in obesity|adipose most abundant gene transcript 2 protein|adipose specific 2|adipose-specific protein 2 |
Swissprots | Q15847 |
Accessions | EAW80313 Q15847 AI401530 AK312031 BAG34968 BC004471 AAH04471 BM789611 BM850559 CD722742 D45370 BAA08226 NM_006829 NP_006820 |
Function | Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin. {ECO:0000269|PubMed:19444912, ECO:0000269|PubMed:23239344}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:23239344}. |
Tissue Specificity | Expressed in adipose tissue (at protein level). Highly expressed in omental and subcutaneous adipose tissues. Expressed in heart, cornea, liver, kidney and spleen. {ECO:0000269|PubMed:23239344, ECO:0000269|Ref.4}. |
Human APM2 peptide - ab95393 from Abcam
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APM2 Control Peptide - AP05309CP-N from Acris Antibodies
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C10orf116 fusion protein - Ag14341 from Proteintech Group
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C10orf116 fusion protein - Ag14875 from Proteintech Group
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Recombinant Human C10orf116, GST-tagged - C10orf116-10346H from Creative Biomart
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Recombinant Human Adipose most abundant gene transcript 2 protein(APM2) - CSB-YP621887HU CSB-EP621887HU CSB-BP621887HU CSB-MP621887HU from Cusabio
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ADIRF Peptide (OEEG01145) - OEEG01145 from Aviva Systems Biology
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APM2 - TP302414 from Acris Antibodies
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Adipose most abundant gene transcript 2 protein (APM2) , Recombinant Protein - MBS1329789 from MyBioSource
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APM2, Peptide - MBS396453 from MyBioSource
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C10ORF116 Peptide, Human - M34GP01612H from Creative Peptides
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APM2 Recombinant Protein Antigen - NBP2-30736PEP from Novus Biologicals
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APM2 peptide - orb108428 from Biorbyt
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