Gene Symbol | DEFB103B |
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Entrez Gene | 55894 |
Alt Symbol | BD-3, DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3 |
Species | Human |
Gene Type | protein-coding |
Description | defensin, beta 103B |
Other Description | beta-defensin 103|beta-defensin 3|defensin, beta 103|defensin-like protein |
Swissprots | Q9NPF6 P81534 Q8NFG6 |
Accessions | P81534 AB037972 BAB40572 AF217245 AAF73853 AF295370 AAG02237 AF301470 AAG22030 AF516673 AAM62424 AJ237673 CAC03097 AY785153 AAV41025 EU918408 ACK99045 NM_018661 NP_061131 |
Function | Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. {ECO:0000269|PubMed:11085990}. |
Subcellular Location | Secreted. |
Tissue Specificity | Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. {ECO:0000269|PubMed:11085990}. |
β-defensin 3 (FL-67) - sc-30115 from Santa Cruz Biotechnology
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β-defensin 3 (K-13) - sc-30934 from Santa Cruz Biotechnology
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β-defensin 3 (L3-18b-E1) - sc-59495 from Santa Cruz Biotechnology
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Anti-DEFB3 / Beta Defensin 3 Antibody - LS-C104293 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody - LS-C306535 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (aa23-67) - LS-C293656 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (N-Terminus) - LS-C35132 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (aa23-33, HRP) - LS-C35131 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (N-Terminus) - LS-C35133 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (aa23-33) - LS-C40649 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody - LS-C83206 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (Biotin) - LS-C104286 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (aa6-22, clone L3-18B-E1) - LS-C127009 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (Internal) - LS-C154890 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody (Biotin) - LS-C189324 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody - LS-C190525 from LifeSpan Bioscience
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Anti-DEFB3 / Beta Defensin 3 Antibody IHC-plus⢠- LS-B86 from LifeSpan Bioscience
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beta-Defensin 3 Antibody - NB200-117 from Novus Biologicals
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beta-Defensin 3 Antibody - AF4435 from Novus Biologicals
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beta-Defensin 3 Antibody - H00055894-B01P from Novus Biologicals
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Anti-DEFB103A antibody produced in mouse - SAB1401766 from Sigma-Aldrich
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Anti-β-Defensin 3 antibody produced in rabbit - D2444 from Sigma-Aldrich
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beta 3 Defensin antibody - GTX19270 from GeneTex
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Human beta -Defensin 3 Antibody - AF4435 from R&D Systems
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Human beta-Defensin 3 Affinity Purified Polyclonal Ab, Goat IgG - AF4435-SP from R&D Systems
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