DEFB103B

Gene Symbol DEFB103B
Entrez Gene 55894
Alt Symbol BD-3, DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3
Species Human
Gene Type protein-coding
Description defensin, beta 103B
Other Description beta-defensin 103|beta-defensin 3|defensin, beta 103|defensin-like protein
Swissprots Q9NPF6 P81534 Q8NFG6
Accessions P81534 AB037972 BAB40572 AF217245 AAF73853 AF295370 AAG02237 AF301470 AAG22030 AF516673 AAM62424 AJ237673 CAC03097 AY785153 AAV41025 EU918408 ACK99045 NM_018661 NP_061131
Function Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. {ECO:0000269|PubMed:11085990}.
Subcellular Location Secreted.
Tissue Specificity Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. {ECO:0000269|PubMed:11085990}.

Human DEFB103A ORF clone(NM_018661.3) - CDCL183911 from Creative Biomart

Species Human
Accession NM_018661.3

Human DEFB103A ORF clone(NM_018661.3) - CDCL183911 from Creative biogene

Species Human

Human DEFB103A ORF clone (NM_001081551.2) - CDCR054694 from Creative biogene

Species Human

Human DEFB103A cDNA Clone(NM_001081551.2) - CDFH004950 from Creative biogene

Species Human
Search more