CALCOCO2

Gene Symbol CALCOCO2
Entrez Gene 10241
Alt Symbol NDP52
Species Human
Gene Type protein-coding
Description calcium binding and coiled-coil domain 2
Other Description antigen nuclear dot 52 kDa protein|calcium-binding and coiled-coil domain-containing protein 2|nuclear domain 10 protein 52|nuclear domain 10 protein NDP52|nuclear dot protein 52
Swissprots E9PBE5 Q13137 Q6IBN9 B4DDT4 B4E0C0 Q53HB5 Q53FQ5 B4DP36 B2RBT0 E7ENK0 Q9BTF7 E7ETP5 B4DDC4
Accessions EAW94707 EAW94708 Q13137 AF085965 AK222666 BAD96386 AK223227 BAD96947 AK293137 BAG56685 AK293329 BAG56845 AK298177 BAG60448 AK303313 BAG64382 AK304024 BAG64939 AK310648 AK314796 BAG37327 AL042638 AL046722 BC004130 AAH04130 BC015893 AAH15893 BE315542 BG773301 BU620013 CR456763 CAG33044 HQ448259 ADQ32739 JF432510 ADZ15727 U22897 AAA75297 XM_011524181 XP_011522483 NM_001261390 NP_001248319 NM_001261391 NP_001248320 NM_001261393 NP_001248322 NM_001261395 NP_001248324 NM_005831 NP_005822
Function May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion. {ECO:0000269|PubMed:17635994}.
Subcellular Location Cytoplasm, perinuclear region. Golgi apparatus. Cytoplasm, cytoskeleton. Note=According to PubMed:7540613, localizes to nuclear dots. According to PubMed:9230084 and PubMed:12869526, it is not a nuclear dot- associated protein but localizes predominantly in the cytoplasm with a coarse-grained distribution preferentially close to the nucleus.
Tissue Specificity Expressed in all tissues tested with highest expression in skeletal muscle and lowest in brain. {ECO:0000269|PubMed:7540613}.

CALCOCO2-Over-expression-Lysate - LY13421a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CALCOCO2 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CALCOCO2 gene

CALCOCO2 293T Cell Transient Overexpression Lysate(Denatured) - H00010241-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

CALCOCO2 293 Cell Lysate - 407968 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

NDP52 Overexpression Lysate (Denatured) - H00010241-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: CALCOCO2 transfected lysate (52.3 KDa) Lane 2: Non-transfected lysate.

NDP52 Overexpression Lysate (Native) - NBL1-08646 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: NDP52 Overexpression Lysate (Adult Normal) [NBL1-08646] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NDP52.

CALCOCO2 (h): 293 Lysate - sc-112224 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

CALCOCO2 Over-expression Lysate Product - GWB-EE1583 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

NDP52 Overexpression Lysate (Denatured) - H00010241-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human CALCOCO2 Knockdown Stable Cell Line - CSC-DC002294 from Creative biogene

Category Cell Line
Species Human
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