CALCOCO2

Gene Symbol CALCOCO2
Entrez Gene 10241
Alt Symbol NDP52
Species Human
Gene Type protein-coding
Description calcium binding and coiled-coil domain 2
Other Description antigen nuclear dot 52 kDa protein|calcium-binding and coiled-coil domain-containing protein 2|nuclear domain 10 protein 52|nuclear domain 10 protein NDP52|nuclear dot protein 52
Swissprots E9PBE5 Q13137 Q6IBN9 B4DDT4 B4E0C0 Q53HB5 Q53FQ5 B4DP36 B2RBT0 E7ENK0 Q9BTF7 E7ETP5 B4DDC4
Accessions EAW94707 EAW94708 Q13137 AF085965 AK222666 BAD96386 AK223227 BAD96947 AK293137 BAG56685 AK293329 BAG56845 AK298177 BAG60448 AK303313 BAG64382 AK304024 BAG64939 AK310648 AK314796 BAG37327 AL042638 AL046722 BC004130 AAH04130 BC015893 AAH15893 BE315542 BG773301 BU620013 CR456763 CAG33044 HQ448259 ADQ32739 JF432510 ADZ15727 U22897 AAA75297 XM_011524181 XP_011522483 NM_001261390 NP_001248319 NM_001261391 NP_001248320 NM_001261393 NP_001248322 NM_001261395 NP_001248324 NM_005831 NP_005822
Function May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion. {ECO:0000269|PubMed:17635994}.
Subcellular Location Cytoplasm, perinuclear region. Golgi apparatus. Cytoplasm, cytoskeleton. Note=According to PubMed:7540613, localizes to nuclear dots. According to PubMed:9230084 and PubMed:12869526, it is not a nuclear dot- associated protein but localizes predominantly in the cytoplasm with a coarse-grained distribution preferentially close to the nucleus.
Tissue Specificity Expressed in all tissues tested with highest expression in skeletal muscle and lowest in brain. {ECO:0000269|PubMed:7540613}.

SignalSilence ® NDP52 siRNA II - 9000 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® NDP52 siRNA I # 8964 (+), or SignalSilence ® NDP52 siRNA II (+), using NDP52 Antibody #9036 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The NDP52 Antibody confirms silencing of NDP52 expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

SignalSilence ® NDP52 siRNA I - 8964 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® NDP52 siRNA I (+), or SignalSilence ® NDP52 siRNA II #9000 (+), using NDP52 Antibody #9036 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The NDP52 Antibody confirms silencing of NDP52 expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

CALCOCO2 CRISPR/Cas9 KO Plasmid (h) - sc-416970 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALCOCO2 HDR Plasmid (h) - sc-416970-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALCOCO2 Double Nickase Plasmid (h) - sc-416970-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALCOCO2 Double Nickase Plasmid (h2) - sc-416970-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALCOCO2 CRISPR Activation Plasmid (h) - sc-416970-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALCOCO2 CRISPR Activation Plasmid (h2) - sc-416970-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALCOCO2 Lentiviral Activation Particles (h) - sc-416970-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALCOCO2 Lentiviral Activation Particles (h2) - sc-416970-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CALCOCO2 siRNA (h) - sc-93738 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CALCOCO2 shRNA Plasmid (h) - sc-93738-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CALCOCO2 shRNA (h) Lentiviral Particles - sc-93738-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NDP52 RNAi - H00010241-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU033821 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5294 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5294 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10457 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10457

CALCOCO2 siRNA (Human) - CRH6928 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CALCOCO2 - MBS8237359 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CALCOCO2 (NM_005831.4) - SHH253729 from Creative biogene

Category siRNA
Species Reactivities Human

Human CALCOCO2 siRNA - orb267430 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CALCOCO2 shRNA Plasmid (Human) - CHH6928 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CALCOCO2 miRNA 3'UTR clone - MiUTR3H-06932 from Creative biogene

Species Reactivities Human
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