CNTNAP2

Gene Symbol CNTNAP2
Entrez Gene 26047
Alt Symbol AUTS15, CASPR2, CDFE, NRXN4, PTHSL1
Species Human
Gene Type protein-coding
Description contactin associated protein-like 2
Other Description cell recognition molecule Caspr2|contactin-associated protein-like 2|homolog of Drosophila neurexin IV
Swissprots Q5H9Q7 Q9UHC6 Q9UQ12 D3DWG2 Q52LV1 Q14DG2
Accessions AAC36298 AAC71656 AAD50520 AAK49901 AAK49902 AAK49903 AAK49904 AAK49905 AAK49906 AAK49907 AAP21885 AAP21888 AAP21890 AAP22353 AAP22358 AAS00355 AAS02006 AAS07427 AAS07479 AAS07480 AAS07543 AAS07562 CAK96045 EAL24417 EAW80082 EAW80083 EAW80084 Q9UHC6 AB020675 BAA74891 AB073883 AF319045 AAK34932 AK000960 AK294098 BAH11672 AK296532 BAH12379 AK315113 BAG37571 BC093780 AAH93780 BC113373 AAI13374 CD625182 CD625192 CR933671 CAI45967 KJ534810 AHW56450 KJ534811 AHW56451 KJ534812 AHW56452 KJ534813 AHW56453 KJ534814 AHW56454 KJ535069 AHW56708 KJ535088 AHW56727 XM_006715919 XP_006715982 NM_014141 NP_054860
Function May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000250|UniProtKB:Q9CPW0}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000250|UniProtKB:Q9CPW0}.
Tissue Specificity Predominantly expressed in nervous system. {ECO:0000269|PubMed:10624965}.
Top Pathways Cell adhesion molecules (CAMs)

Caspr2 Antibody - 3731 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from mouse and rat brain using Caspr2 Antibody.

CASPR2 (H-10) - sc-398454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CASPR2 (H-10): sc-398454. Western blot analysis of CASPR2 expression in human hippocampus tissue extract.

CASPR2 (A-16) - sc-11180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CASPR2 (G-17) - sc-11179 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CASPR2 (H-100) - sc-368215 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CASPR2 (N-16) - sc-11178 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CASPR2 (N-16): sc-11178. Western blot analysis of CASPR2 expression in human brain tissue extract.

Anti-Caspr2 antibody - ab33994 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Caspr2 antibody (ab33994) at 1 µg/mlLane 1 : Brain (Mouse) Tissue Lysate at 20 µgLane 2 : Brain (Rat) Tissue Lysate at 20 µgLane 3 : Brain (Human) Tissue Lysate at 20 µgLane 4 : Sciatic Nerve (Mouse) Lysate at 7.5 µgLane 5 : Sciatic Nerve (Rat) Lysate at 20 µgSecondary IRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-Caspr2 antibody - ab153856 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Caspr2 antibody (ab153856) at 1/5000 dilution + Molt-4 whole cell lysate at 30 µg

Anti-Caspr2 antibody - ab50206 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Caspr2 antibody (ab50206) at 1/1000 dilutionLane 1 : Normal rat lung homogenateLane 2 : Normal rat lung plasma membrane fractionLane 3 : Tumor (13762) rat lung homogenateLane 4 : Tumor (13762) rat lung plasma membrane fractionLane 5 : Rat brain homogenateLysates/proteins at 10 µg per lane.SecondaryHRP conjugated donkey anti-rabbitdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Caspr2 antibody - ab104525 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-Caspr2 antibody - ab93228 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Caspr2 antibody (ab93228) at 1/100 dilution + CEM cell line lysates at 35 µg

Anti-Caspr2 antibody - ab172456 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Caspr2 antibody (ab172456) at 1 µg/mlLane 1 : Caspr2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-Caspr2 antibody [EPR8738] - ab137052 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8738
Anti-Caspr2 antibody [EPR8738] (ab137052) at 1/1000 dilution (purified) + Human glioma tissue lysate at 20 µgSecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-Caspr2 antibody [S67-25] - ab105581 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone S67-25
Immunohistochemical detection of CASPR2 in frozen sections of Mouse brain extract using ab105581.

Anti-CNTNAP2 / CASPR2 Antibody (Glu1320) - LS-C79747 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CNTNAP2 / CASPR2 Antibody (clone S67-25) - LS-C153152 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S67-25

Anti-CNTNAP2 / CASPR2 Antibody (Internal, APC) - LS-C218837 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNTNAP2 / CASPR2 Antibody (Internal, AP) - LS-C218836 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNTNAP2 / CASPR2 Antibody (Internal, Biotin) - LS-C218838 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNTNAP2 / CASPR2 Antibody (Extracellular Domain, clone S67-25, Atto 488) - LS-C228260 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S67-25

Anti-CNTNAP2 / CASPR2 Antibody (Internal, FITC) - LS-C218839 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNTNAP2 / CASPR2 Antibody (Extracellular Domain, clone S67-25, Atto 565) - LS-C228261 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S67-25

Anti-CNTNAP2 / CASPR2 Antibody (Extracellular Domain, clone S67-25, Atto 390) - LS-C228258 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone S67-25

Anti-CNTNAP2 / CASPR2 Antibody (Internal, PE) - LS-C218841 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNTNAP2 / CASPR2 Antibody (Internal, Azide-free, HRP) - LS-C218840 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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