SLC6A19

Gene Symbol SLC6A19
Entrez Gene 340024
Alt Symbol B0AT1, HND
Species Human
Gene Type protein-coding
Description solute carrier family 6 (neutral amino acid transporter), member 19
Other Description sodium-dependent amino acid transporter system B0|sodium-dependent neutral amino acid transporter B(0)AT1|solute carrier family 6 (neurotransmitter transporter), member 19|solute carrier family 6 member 19|system B(0) neutral amino acid transporter AT1|system B0 neutral amino acid transporter
Swissprots Q695T7 A8K446
Accessions EAX08174 EAX08175 Q695T7 AI015994 AK000687 AK091954 AK096054 BAG53204 AK123779 BAG53960 AK290811 BAF83500 AY591756 AAT66171 AY596807 AAT42127 BC146290 AAI46291 BC148801 AAI48802 NM_001003841 NP_001003841
Function Transporter that mediates epithelial resorption of neutral amino acids across the apical membrane of epithelial cells in the kidney and intestine. It appears that leucine is the preferred substrate, but all large neutral non-aromatic L-amino acids bind to this transporter. Uptake of leucine is sodium- dependent. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Robust expression in kidney and small intestine, with minimal expression in pancreas. Also expressed in stomach, liver, duodenum, ileocecum, colon and prostate. Not detected in testis, whole brain, cerebellum, fetal liver, spleen, skeletal muscle, uterus, heart or lung. {ECO:0000269|PubMed:15286787, ECO:0000269|PubMed:15286788}.
Top Pathways Protein digestion and absorption, Mineral absorption

SLC6A19 CRISPR/Cas9 KO Plasmid (h) - sc-404564 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC6A19 HDR Plasmid (h) - sc-404564-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC6A19 Double Nickase Plasmid (h) - sc-404564-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC6A19 Double Nickase Plasmid (h2) - sc-404564-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC6A19 CRISPR Activation Plasmid (h) - sc-404564-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC6A19 CRISPR Activation Plasmid (h2) - sc-404564-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC6A19 Lentiviral Activation Particles (h) - sc-404564-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC6A19 Lentiviral Activation Particles (h2) - sc-404564-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC6A19 siRNA (h) - sc-91732 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC6A19 shRNA Plasmid (h) - sc-91732-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC6A19 shRNA (h) Lentiviral Particles - sc-91732-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC6A19 RNAi - H00340024-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU031461 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19679 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19679 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC6A19 siRNA (Human) - CRJ7322 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC6A19 - MBS827639 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Slc6a19 (NM_001003841.2) - SHH411904 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC6A19 siRNA - orb277823 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC6A19 shRNA Plasmid (Human) - CHJ7322 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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