LPP

Gene Symbol LPP
Entrez Gene 4026
Alt Symbol -
Species Human
Gene Type protein-coding
Description LIM domain containing preferred translocation partner in lipoma
Other Description LIM protein|lipoma-preferred partner
Swissprots A1L4L6 Q93052 Q8NFX5 D3DNV6
Accessions AAC50739 CAA03407 CAB59169 CAC94500 EAW78127 EAW78128 EAW78129 EAW78130 EAW78131 EAW78132 EAW78133 EAW78134 Q93052 AA813328 AI126032 AK055214 AK123506 AK302959 BAH13857 AK304035 BAH14096 AL833171 AW301088 BC042960 BC130584 AAI30585 BC144076 AAI44077 BG192042 BX474180 BX641108 CD697098 CR457074 CAG33355 U29116 U49957 AAC50738 XM_005247446 XP_005247503 XM_005247450 XP_005247507 XM_005247451 XP_005247508 XM_005247453 XP_005247510 XM_011512820 XP_011511122 XM_011512821 XP_011511123 XM_011512822 XP_011511124 XM_011512823 XP_011511125 XM_011512824 XP_011511126 XM_011512825 XP_011511127 XM_011512826 XP_011511128 XM_011512827 XP_011511129 XM_011512828 XP_011511130 XM_011512829 XP_011511131 XM_011512830 XP_011511132 XM_011512831 XP_011511133 XM_011512832 XP_011511134 XM_011512833 XP_011511135 XM_011512834 XP_011511136 XM_011512835 XP_011511137 XM_011512836 XP_011511138 NM_001167671 NP_001161143 NM_001167672 NP_001161144 NM_005578 NP_005569
Function May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus. {ECO:0000269|PubMed:10637295, ECO:0000269|Ref.2}.
Subcellular Location Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1.
Tissue Specificity Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes. {ECO:0000269|PubMed:10637295, ECO:0000269|PubMed:8812423}.

LPP (8B3A11) Mouse mAb - 3389 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 8B3A11
Western blot analysis of extracts from various cell types using LPP (8B3A110) Mouse mAb.

LPP (8B3A11) - sc-101434 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LPP (8B3A11): sc-101434. Immunofluorescence staining of HeLa cells showing cytoplasmic localization (green), actin filaments (red) are labeled with DY-554 phalloidin.

LPP (E-14) - sc-27313 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LPP (N-20) - sc-27312 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LPP (N-20): sc-27312. Western blot analysis of LPP expression in HeLa (A) and Caco-2 (B) whole cell lysates.

Anti-LPP antibody - ab87212 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPP antibody (ab87212) at 1 µg/ml (in 5% skim milk / PBS buffer) + COLO205 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-LPP antibody - ab187350 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-LPP antibody (ab187350) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : HeLa total cell extract

Anti-LPP antibody - ab128166 from Abcam

Prices $428.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab128166, at 1/250 dilution, staining LPP in paraffin-embedded Human Osteosarcoma tissue by Immunohistochemistry. Detection: DAB staining.

Anti-LPP antibody - ab191016 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LPP antibody (ab191016) at 0.5 µg/mlLane 1 : SMMC cell lysateLane 2 : HeLa cell lysateLane 3 : SW620 cell lysateLane 4 : A549 cell lysateLane 5 : SKOV cell lysateLane 6 : MCF-7 cell lysate

Anti-LPP antibody [8B3A11] - ab63621 from Abcam

Host Mouse
Clonality Monoclonal
Clone 8B3A11
Overlay histogram showing HeLa cells stained with ab63621 (red line). The cells were fixed with 80% methanol (5 min)/ and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab63621, 1/10000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 4% formaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-LPP antibody [EPR6478] - ab126608 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6478
All lanes : Anti-LPP antibody [EPR6478] (ab126608) at 1/10000 dilutionLane 1 : Caco 2 cell lysateLane 2 : HeLa cell lysateLane 3 : NIH 3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-LPP antibody [EPR6479(2)] - ab133651 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6479(2)
All lanes : Anti-LPP antibody [EPR6479(2)] (ab133651) at 1/1000 dilutionLane 1 : Caco2 cell lysateLane 2 : 293T cell lysateLane 3 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-LIM Protein / LPP Antibody (aa374-390) - LS-C3078 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIM Protein / LPP Antibody (aa1-109) - LS-C8490 from LifeSpan Bioscience

Prices $635.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-LIM Protein / LPP Antibody (aa138-261, clone 1D4B) - LS-C189812 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D4B

Anti-LIM Protein / LPP Antibody (aa107-156) - LS-C102546 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LPP antibody LS-C102546 Western blot of COLO205 cell lysate.

Anti-LIM Protein / LPP Antibody (aa310-323) - LS-C108940 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
LPP antibody (0.1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-LIM Protein / LPP Antibody (aa75-125) - LS-C286933 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human LPP by Immunohistochemistry. Sample: FFPE section of human osteosarcoma. Antibody: Affinity purified rabbit anti-LPP used at a dilution of 1:250.

Anti-LIM Protein / LPP Antibody (aa291-307) - LS-C313165 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of LIM Protein / LPP antibody. Lane 1: SMMC Cell Lysate. Lane 2: HELA Cell Lysate. Lane 3: SW620 Cell Lysate. Lane 4: A549 Cell Lysate. Lane 5: SKOV Cell Lysate. Lane 6: MCF-7 Cell Lysate..

Anti-LIM Protein / LPP Antibody (aa75-125) - LS-C286129 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human LPP by Immunohistochemistry. Sample: FFPE section of human osteosarcoma. Antibody: Affinity purified rabbit anti-LPP used at a dilution of 1:200 (1 Detection: DAB.

Anti-LIM Protein / LPP Antibody (Internal, clone EPR6479(2)) - LS-C154597 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6479(2)
Western blot analysis on (A) Caco-2, (B) 293T, and (C) HeLa cell lysates using anti-LPP antibody.

Anti-LIM Protein / LPP Antibody (aa1-109) - LS-C344846 from LifeSpan Bioscience

Prices $475.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemical staining of a rat cardiac fibroblast using anti-Lipoma Preferred Partner, pAb (IG-817) (LPP; red fluorescence) and a green-fluorescent phalloidin derivative staining filamentous actin. LPP is a protein related to the cytoskeletal and focal adhesion protein zyxin.

Anti-LIM Protein / LPP Antibody (N-Terminus, clone EPR6478) - LS-C152304 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6478
IHC of paraffin-embedded human kidney tissue using anti-LPP antibody.

Anti-LIM Protein / LPP Antibody IHC-plus™ - LS-B3472 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Anti-LPP antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3472 dilution 1:200.

LPP Antibody (8B3A11) - NBP1-47516 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8B3A11

LPP Antibody (691121) - MAB6927 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 691121
Western blot shows lysates of MDA‑MB‑468 human breast cancer cell line and C2C12 mouse myoblast cell line. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human LPP Monoclonal Antibody (Catalog # MAB6927) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for LPP at approximately 80 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
Search more