Gene Symbol | CREB3L1 |
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Entrez Gene | 90993 |
Alt Symbol | OASIS |
Species | Human |
Gene Type | protein-coding |
Description | cAMP responsive element binding protein 3-like 1 |
Other Description | BBF-2 homolog|cAMP-responsive element-binding protein 3-like protein 1|cyclic AMP-responsive element-binding protein 3-like protein 1|old astrocyte specifically-induced substance |
Swissprots | Q8N2D5 Q96BA8 Q96CP0 |
Accessions | EAW68010 Q96BA8 AB063321 BAC01278 AF055009 AK075538 BAC11681 AK314072 BAG36772 BC014097 AAH14097 BC015781 AAH15781 BQ953032 CF131922 DA693632 DQ895809 ABM86735 EU176365 ABW03816 XM_006718380 XP_006718443 NM_052854 NP_443086 |
Function | Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12054625, ECO:0000269|PubMed:16417584}; Single-pass type II membrane protein {ECO:0000269|PubMed:12054625, ECO:0000269|PubMed:16417584}. |
Tissue Specificity | Ubiquitously expressed with high levels in pancreas and prostate. Expressed at relatively lower levels in brain. {ECO:0000269|PubMed:12054625}. |
Top Pathways | cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway |
Human CREB3L1 full length protein - ab153567 from Abcam
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OASIS / CREB3L1 Antibody Blocking Peptide - LS-E8140 from LifeSpan Bioscience
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OASIS / CREB3L1 Antibody Blocking Peptide - LS-E8317 from LifeSpan Bioscience
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OASIS / CREB3L1 Antibody Blocking Peptide - LS-E12893 from LifeSpan Bioscience
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OASIS / CREB3L1 Antibody Blocking Peptide - LS-E25943 from LifeSpan Bioscience
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OASIS/CREB3L1 Recombinant Protein - H00090993-P01 from Novus Biologicals
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OASIS/CREB3L1 Peptide - P1837 from Novus Biologicals
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CREB3L1-Antibody-Center-Blocking-peptide - BP12890c from Abgent, a WuXi AppTec company
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OASIS-Antibody-C-term-Blocking-Peptide - BP6229a from Abgent, a WuXi AppTec company
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CREB3L1-Antibody-C-term-Blocking-Peptide - BP6589b from Abgent, a WuXi AppTec company
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CREB3L1 blocking peptide - GTX89497-PEP from GeneTex
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Human CREB3L1 protein (His Tag) - orb138621 from Biorbyt
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CREB3L1 Blocking Peptide - 33R-3088 from Fitzgerald
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CREB3L1 Blocking Peptide - 33R-5823 from Fitzgerald
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CREB3L1 Peptide - AC21-0772-P from Abcore
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CREB3L1 / OASIS - H00090993-P01-10 from Acris Antibodies
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CREB3L1 / OASIS - H00090993-P01-25 from Acris Antibodies
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OASIS Peptide - 45-989P from ProSci
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CREB3L1,OASIS fusion protein - ag13260 from Proteintech Group
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CREB3L1,OASIS fusion protein - Ag1757 from Proteintech Group
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CREB3L1,OASIS fusion protein - ag13312 from Proteintech Group
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Human CREB3L1 / OASIS Protein (aa 396-519, His Tag) - 12712-H08H-100 from Sino Biological
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Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 1(CREB3L1) - CSB-YP856900HU CSB-EP856900HU CSB-BP856900HU CSB-MP856900HU from Cusabio
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CREB3L1 Protein - abx164915 from Abbexa
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CREB3L1 / OASIS (full length, N-term HIS tag) - TP760562 from Acris Antibodies
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