| Gene Symbol |
YWHAH
|
| Entrez Gene |
7533
|
| Alt Symbol |
YWHA1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
|
| Other Description |
14-3-3 eta|14-3-3 protein eta|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
|
| Swissprots |
Q04917
|
| Accessions |
BAA11418 CAA56676 EAW60001 EAW60002 EAW60003 Q04917 AK307750 AK312650 BAG35533 AY007132 AAG01995 BC003047 AAH03047 CR456612 CAG30498 CU013208 CAK54639 CU013496 CAK54938 L08439 L20422 AAA35483 S80794 AAB36036 X57345 CAA40620 X78138 CAA55017 NM_003405 NP_003396
|
| Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. {ECO:0000269|PubMed:12177059}.
|
| Tissue Specificity |
Expressed mainly in the brain and present in other tissues albeit at lower levels.
|
| Top Pathways |
Cell cycle, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway, Epstein-Barr virus infection
|