Gene Symbol | RAP2B |
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Entrez Gene | 5912 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAP2B, member of RAS oncogene family |
Other Description | ras-related protein Rap-2b|small GTP binding protein |
Swissprots | Q9CXG0 P17964 Q96EG5 P61225 |
Accessions | EAW78771 P61225 AF493915 AAM12629 AI718675 AL713766 CAI46163 AW997098 BC012362 AAH12362 BF965860 BI551390 BQ378964 BU507815 BU860799 BX116683 BX355341 CB116910 DQ891702 ABM82628 HY071303 X52987 CAA37178 NM_002886 NP_002877 |
Function | Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells. {ECO:0000269|PubMed:11877431, ECO:0000269|PubMed:15143162, ECO:0000269|PubMed:16540189}. |
Subcellular Location | Recycling endosome membrane {ECO:0000269|PubMed:16540189}; Lipid-anchor {ECO:0000269|PubMed:16540189}; Cytoplasmic side {ECO:0000269|PubMed:16540189}. Note=Associated with red blood cells-released vesicles. |
Tissue Specificity | Expressed in red blood cells (at protein level). {ECO:0000269|PubMed:16540189}. |
Human RAP2B full length protein - ab140538 from Abcam
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Human RAP2B full length protein - ab88159 from Abcam
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RAP2B Antibody Blocking Peptide - LS-E5023 from LifeSpan Bioscience
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RAP2B Antibody Blocking Peptide - LS-E23465 from LifeSpan Bioscience
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Rap2B Recombinant Protein - H00005912-P01 from Novus Biologicals
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Recombinant Human Rap2B Protein - NBP2-23396 from Novus Biologicals
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RAP2B-Antibody-Center-Blocking-Peptide - BP17426c from Abgent, a WuXi AppTec company
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Human RAP2B protein - orb169165 from Biorbyt
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RAP2B protein (His tag) - 80R-2670 from Fitzgerald
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Human RAP2B Protein - abx060029 from Abbexa
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RAP2B - AR00162PU-N from Acris Antibodies
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RAP2B (1-183, His-tag) - AR50790PU-N from Acris Antibodies
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RAP2B (1-183, His-tag) - AR50790PU-S from Acris Antibodies
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RAP2B - H00005912-P01-10 from Acris Antibodies
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RAP2B - H00005912-P01-25 from Acris Antibodies
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RAP2B, 1-183aa, Human, His tag, E.coli - 01-P1966 from ARP American Research Products
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RAP2B fusion protein - Ag9331 from Proteintech Group
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RAP2B fusion protein - Ag9651 from Proteintech Group
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RAP2B Human - PRPS-1371 from NeoScientific
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Recombinant Human RAP2B - RAP2B-30505TH from Creative Biomart
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Recombinant Human RAP2B, His-tagged - RAP2B-31291TH from Creative Biomart
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Recombinant Human RAP2B, His-tagged - RAP2B-7522H from Creative Biomart
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Recombinant Human RAP2B, GST-tagged - RAP2B-2179H from Creative Biomart
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Recombinant Human Ras-related protein Rap-2b(RAP2B) - CSB-YP019327HU CSB-EP019327HU CSB-BP019327HU CSB-MP019327HU from Cusabio
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RAP2B, 1-183aa, Human, His tag, E.coli - ATGP1966 from ATGen
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