Gene Symbol | RAP2B |
---|---|
Entrez Gene | 5912 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAP2B, member of RAS oncogene family |
Other Description | ras-related protein Rap-2b|small GTP binding protein |
Swissprots | Q9CXG0 P17964 Q96EG5 P61225 |
Accessions | EAW78771 P61225 AF493915 AAM12629 AI718675 AL713766 CAI46163 AW997098 BC012362 AAH12362 BF965860 BI551390 BQ378964 BU507815 BU860799 BX116683 BX355341 CB116910 DQ891702 ABM82628 HY071303 X52987 CAA37178 NM_002886 NP_002877 |
Function | Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells. {ECO:0000269|PubMed:11877431, ECO:0000269|PubMed:15143162, ECO:0000269|PubMed:16540189}. |
Subcellular Location | Recycling endosome membrane {ECO:0000269|PubMed:16540189}; Lipid-anchor {ECO:0000269|PubMed:16540189}; Cytoplasmic side {ECO:0000269|PubMed:16540189}. Note=Associated with red blood cells-released vesicles. |
Tissue Specificity | Expressed in red blood cells (at protein level). {ECO:0000269|PubMed:16540189}. |
Rap 2B CRISPR/Cas9 KO Plasmid (h) - sc-403292 from Santa Cruz Biotechnology
|
||||||||
Rap 2B HDR Plasmid (h) - sc-403292-HDR from Santa Cruz Biotechnology
|
||||||||
Rap 2B Double Nickase Plasmid (h) - sc-403292-NIC from Santa Cruz Biotechnology
|
||||||||
Rap 2B Double Nickase Plasmid (h2) - sc-403292-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Rap 2B CRISPR Activation Plasmid (h) - sc-403292-ACT from Santa Cruz Biotechnology
|
||||||||
Rap 2B CRISPR Activation Plasmid (h2) - sc-403292-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Rap 2B Lentiviral Activation Particles (h) - sc-403292-LAC from Santa Cruz Biotechnology
|
||||||||
Rap 2B Lentiviral Activation Particles (h2) - sc-403292-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Rap 2B siRNA (h) - sc-43515 from Santa Cruz Biotechnology
|
||||||||
Rap 2B shRNA Plasmid (h) - sc-43515-SH from Santa Cruz Biotechnology
|
||||||||
Rap 2B shRNA (h) Lentiviral Particles - sc-43515-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN17951 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17951 from Sigma-Aldrich
|
||||||||
RAP2B siRNA (Human) - CRH3998 from Cohesion Biosciences
|
||||||||
Rap2B RNAi - H00005912-R01 from Novus Biologicals
|
||||||||
RAP2B - MBS8200391 from MyBioSource
|
||||||||
shRNA set against Human RAP2B (NM_002886.2) - SHH389628 from Creative biogene
|
||||||||
shRNA set against Human RAP2B(NM_002886.2) - SHR164472 from Creative biogene
|
||||||||
Human RAP2B siRNA - orb264500 from Biorbyt
|
||||||||
RAP2B shRNA Plasmid (Human) - CHH3998 from Cohesion Biosciences
|
||||||||
RAP2B miRNA 3'UTR clone - MiUTR1H-08625 from Creative biogene
|