Gene Symbol | NPPA |
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Entrez Gene | 4878 |
Alt Symbol | ANF, ANP, ATFB6, ATRST2, CDD, CDD-ANF, CDP, PND |
Species | Human |
Gene Type | protein-coding |
Description | natriuretic peptide A |
Other Description | atriopeptin|cardiodilatin|cardiodilatin-related peptide|cardionatrin|natriuretic peptide precursor A|natriuretic peptides A|prepronatriodilatin |
Swissprots | Q5JZE1 P01160 Q13766 |
Accessions | AAA35528 AAA35529 AAB59379 ACA05916 CAA25699 CAA25700 EAW71717 P01160 AA779538 BC005893 AAH05893 DQ893115 ABM84041 DQ896389 ABM87388 EU176780 ABW03581 K02044 AAA51730 M30262 AAA35669 NM_006172 NP_006163 |
Function | Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. {ECO:0000269|PubMed:1672777}. |
Subcellular Location | Secreted. |
Human ANP full length protein - ab114317 from Abcam
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Human ANP peptide - ab42331 from Abcam
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Human proANP peptide - ab42274 from Abcam
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Human proANP peptide - ab42275 from Abcam
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Human proANP peptide - ab42277 from Abcam
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Human proANP peptide - ab42339 from Abcam
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Human proANP peptide - ab27128 from Abcam
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Human proANP peptide - ab42236 from Abcam
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Human proANP peptide - ab42346 from Abcam
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Rat ANP peptide - ab42248 from Abcam
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Rat proANP peptide - ab42343 from Abcam
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NPPA / ANP Antibody Blocking Peptide - LS-E27777 from LifeSpan Bioscience
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NPPA / ANP Antibody Blocking Peptide - LS-E9627 from LifeSpan Bioscience
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Recombinant Human proANP Protein - H00004878-P01 from Novus Biologicals
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NPPA-Antibody-N-term-Blocking-Peptide - BP8534a from Abgent, a WuXi AppTec company
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ANP Protein - GTX109255-pro from GeneTex
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Human NPPA protein - orb246768 from Biorbyt
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ANP (1-28) peptide - orb99611 from Biorbyt
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ANP peptide - orb72326 from Biorbyt
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ANP (1-30) Peptide - abx064383 from Abbexa
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Human ANP Protein - abx065481 from Abbexa
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Human ANP Protein - abx065485 from Abbexa
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ANP Peptide - AC21-2589-P from Abcore
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Atrial Natriuretic Factor (ANF) - H00004878-P01-10 from Acris Antibodies
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Atrial Natriuretic Factor (ANF) - H00004878-P01-25 from Acris Antibodies
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