Gene Symbol | Agr2 |
---|---|
Entrez Gene | 23795 |
Alt Symbol | Agr2h, Gob-4, HAG-2, XAG-2, mAG-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | anterior gradient 2 |
Other Description | AG-2|anterior gradient 2 homolog|anterior gradient protein 2 homolog|protein Gob-4|secreted cement gland protein XAG-2 homolog |
Swissprots | O88312 A2CGA2 |
Accessions | EDL36857 O88312 AB016592 BAA32044 AF044262 AAC72705 AK007677 BAB25181 AK008296 BC013334 AAH13334 NM_011783 NP_035913 |
Function | Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:19359471}. |
Tissue Specificity | Expressed in lung, skeletal muscle, testis, liver, stomach, colon, small intestine, the goblet cells of the intestine and the mucuous neck cells of the stomach. {ECO:0000269|PubMed:10095068, ECO:0000269|PubMed:9790916}. |