Gene Symbol | Agr2 |
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Entrez Gene | 23795 |
Alt Symbol | Agr2h, Gob-4, HAG-2, XAG-2, mAG-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | anterior gradient 2 |
Other Description | AG-2|anterior gradient 2 homolog|anterior gradient protein 2 homolog|protein Gob-4|secreted cement gland protein XAG-2 homolog |
Swissprots | O88312 A2CGA2 |
Accessions | EDL36857 O88312 AB016592 BAA32044 AF044262 AAC72705 AK007677 BAB25181 AK008296 BC013334 AAH13334 NM_011783 NP_035913 |
Function | Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:19359471}. |
Tissue Specificity | Expressed in lung, skeletal muscle, testis, liver, stomach, colon, small intestine, the goblet cells of the intestine and the mucuous neck cells of the stomach. {ECO:0000269|PubMed:10095068, ECO:0000269|PubMed:9790916}. |
AGR2 CRISPR/Cas9 KO Plasmid (m) - sc-423838 from Santa Cruz Biotechnology
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AGR2 HDR Plasmid (m) - sc-423838-HDR from Santa Cruz Biotechnology
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AGR2 Double Nickase Plasmid (m) - sc-423838-NIC from Santa Cruz Biotechnology
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AGR2 Double Nickase Plasmid (m2) - sc-423838-NIC-2 from Santa Cruz Biotechnology
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AGR2 CRISPR Activation Plasmid (m) - sc-423838-ACT from Santa Cruz Biotechnology
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AGR2 CRISPR Activation Plasmid (m2) - sc-423838-ACT-2 from Santa Cruz Biotechnology
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AGR2 Lentiviral Activation Particles (m) - sc-423838-LAC from Santa Cruz Biotechnology
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AGR2 Lentiviral Activation Particles (m2) - sc-423838-LAC-2 from Santa Cruz Biotechnology
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AGR2 siRNA (m) - sc-61957 from Santa Cruz Biotechnology
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AGR2 shRNA Plasmid (m) - sc-61957-SH from Santa Cruz Biotechnology
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AGR2 shRNA (m) Lentiviral Particles - sc-61957-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN26415 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26415 from Sigma-Aldrich
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AGR2 siRNA (Mouse) - CRM4529 from Cohesion Biosciences
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AGR2 - MBS8224949 from MyBioSource
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shRNA set against Mouse AGR2 (NM_011783.2) - SHH233434 from Creative biogene
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shRNA set against Mouse Agr2(NM_011783.2) - SHG045919 from Creative biogene
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Mouse AGR2 siRNA - orb284005 from Biorbyt
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AGR2 shRNA Plasmid (Mouse) - CHM4529 from Cohesion Biosciences
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AGR2 miRNA 3'UTR clone - MiUTR1M-01297 from Creative biogene
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