Gene Symbol |
Agr2
|
Entrez Gene |
23795
|
Alt Symbol |
Agr2h, Gob-4, HAG-2, XAG-2, mAG-2
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
anterior gradient 2
|
Other Description |
AG-2|anterior gradient 2 homolog|anterior gradient protein 2 homolog|protein Gob-4|secreted cement gland protein XAG-2 homolog
|
Swissprots |
O88312 A2CGA2
|
Accessions |
EDL36857 O88312 AB016592 BAA32044 AF044262 AAC72705 AK007677 BAB25181 AK008296 BC013334 AAH13334 NM_011783 NP_035913
|
Function |
Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (By similarity). {ECO:0000250}.
|
Subcellular Location |
Secreted {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:19359471}.
|
Tissue Specificity |
Expressed in lung, skeletal muscle, testis, liver, stomach, colon, small intestine, the goblet cells of the intestine and the mucuous neck cells of the stomach. {ECO:0000269|PubMed:10095068, ECO:0000269|PubMed:9790916}.
|