ACSL1

Gene Symbol ACSL1
Entrez Gene 2180
Alt Symbol ACS1, FACL1, FACL2, LACS, LACS1, LACS2
Species Human
Gene Type protein-coding
Description acyl-CoA synthetase long-chain family member 1
Other Description LACS 1|LACS 2|acyl-CoA synthetase 1|fatty-acid-Coenzyme A ligase, long-chain 1|fatty-acid-Coenzyme A ligase, long-chain 2|lignoceroyl-CoA synthase|long-chain acyl-CoA synthetase 1|long-chain acyl-CoA synthetase 2|long-chain fatty acid-CoA ligase 2|long-chain fatty-acid-coenzyme A ligase 1|long-chain-fatty-acid--CoA ligase 1|palmitoyl-CoA ligase 1|palmitoyl-CoA ligase 2|paltimoyl-CoA ligase 1
Swissprots Q8TA99 P41215 Q8N8V7 D3DP57 P33121 B7Z452
Accessions CBF64949 CBU89820 EAX04662 EAX04663 EAX04664 EAX04665 P33121 AK096117 BAC04704 AK292798 BAF85487 AK296550 BAH12385 AK296826 BAH12438 AK303486 BAG64522 BC026290 AAH26290 BC033479 BC050073 AAH50073 BG680610 BG773086 BI461964 BM982557 D10040 BAA00931 DC344113 DQ083028 AAZ30711 DQ083029 AAZ30712 L09229 AAB00959 XM_005262828 XP_005262885 XM_005262829 XP_005262886 XM_005262831 XP_005262888 XM_011531740 XP_011530042 XM_011531741 XP_011530043 XM_011531742 XP_011530044 XM_011531743 XP_011530045 NM_001286708 NP_001273637 NM_001286710 NP_001273639 NM_001286711 NP_001273640 NM_001286712 NP_001273641 NM_001995 NP_001986
Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
Subcellular Location Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Tissue Specificity Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas. {ECO:0000269|PubMed:10548543}.
Top Pathways Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation

ACSL1 CRISPR/Cas9 KO Plasmid (h) - sc-402922 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSL1 HDR Plasmid (h) - sc-402922-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSL1 Double Nickase Plasmid (h) - sc-402922-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSL1 Double Nickase Plasmid (h2) - sc-402922-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSL1 CRISPR Activation Plasmid (h) - sc-402922-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSL1 CRISPR Activation Plasmid (h2) - sc-402922-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSL1 Lentiviral Activation Particles (h) - sc-402922-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSL1 Lentiviral Activation Particles (h2) - sc-402922-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACSL1 siRNA (h) - sc-60615 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACSL1 shRNA Plasmid (h) - sc-60615-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACSL1 shRNA (h) Lentiviral Particles - sc-60615-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACSL1 RNAi - H00002180-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU093631 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2752 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2752 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09905 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09905

ACSL1 siRNA (Human) - CRH1518 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACSL1 - MBS8211615 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ACSL1(NM_001995.2) - SHG035421 from Creative biogene

Category siRNA
Species Reactivities Human

ACSL1 shRNA Plasmid (Human) - CHH1518 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ACSL1 miRNA 3'UTR clone - MiUTR1H-00121 from Creative biogene

Species Reactivities Human
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