| Gene Symbol |
HIST3H2BB
|
| Entrez Gene |
128312
|
| Alt Symbol |
H2Bb
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 3, H2bb
|
| Other Description |
H2B type 12|histone 3, H2bb|histone H2B type 3-B
|
| Swissprots |
Q5TA30 Q3ZCP6 A4FU05 Q8N257
|
| Accessions |
AAN59962 EAW69879 Q8N257 AK091220 BAC03613 BC100855 AAI00856 BC100856 AAI00857 BC100857 AAI00858 BC100858 AAI00859 BC137467 AAI37468 BC137468 AAI37469 NM_175055 NP_778225
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism
|
