Gene Symbol | HIST3H2BB |
---|---|
Entrez Gene | 128312 |
Alt Symbol | H2Bb |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 3, H2bb |
Other Description | H2B type 12|histone 3, H2bb|histone H2B type 3-B |
Swissprots | Q5TA30 Q3ZCP6 A4FU05 Q8N257 |
Accessions | AAN59962 EAW69879 Q8N257 AK091220 BAC03613 BC100855 AAI00856 BC100856 AAI00857 BC100857 AAI00858 BC100858 AAI00859 BC137467 AAI37468 BC137468 AAI37469 NM_175055 NP_778225 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 3 H2BB CRISPR/Cas9 KO Plasmid (h) - sc-414320 from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB HDR Plasmid (h) - sc-414320-HDR from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB Double Nickase Plasmid (h) - sc-414320-NIC from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB Double Nickase Plasmid (h2) - sc-414320-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB CRISPR Activation Plasmid (h) - sc-414320-ACT from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB CRISPR Activation Plasmid (h2) - sc-414320-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB Lentiviral Activation Particles (h) - sc-414320-LAC from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB Lentiviral Activation Particles (h2) - sc-414320-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB siRNA (h) - sc-105518 from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB shRNA Plasmid (h) - sc-105518-SH from Santa Cruz Biotechnology
|
||||||||
Histone cluster 3 H2BB shRNA (h) Lentiviral Particles - sc-105518-V from Santa Cruz Biotechnology
|
||||||||
HIST3H2BB RNAi - H00128312-R01 from Novus Biologicals
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN10118 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10118 from Sigma-Aldrich
|
||||||||
HIST3H2BB siRNA (Human) - CRJ4951 from Cohesion Biosciences
|
||||||||
HIST3H2BB - MBS8210336 from MyBioSource
|
||||||||
shRNA set against Human Hist3h2bb (NM_175055.2) - SHH313005 from Creative biogene
|
||||||||
shRNA set against Human HIST3H2BB(NM_175055.2) - SHH123905 from Creative biogene
|
||||||||
Human HIST3H2BB siRNA - orb275452 from Biorbyt
|
||||||||
HIST3H2BB shRNA Plasmid (Human) - CHJ4951 from Cohesion Biosciences
|
||||||||
HIST3H2BB miRNA 3'UTR clone - MiUTR1H-04572 from Creative biogene
|