| Gene Symbol | PAX4 |
|---|---|
| Entrez Gene | 5078 |
| Alt Symbol | KPD, MODY9 |
| Species | Human |
| Gene Type | protein-coding |
| Description | paired box 4 |
| Other Description | paired box gene 4|paired box protein Pax-4|paired domain gene 4 |
| Swissprots | O95161 Q6B0H0 O43316 |
| Accessions | EAL24318 EAW83633 EAW83634 O43316 AB008913 BAA24506 AF043978 AAD02289 BC074761 AAH74761 BC107149 AAI07150 BC107150 AAI07151 DQ442656 ABD97848 EU446646 ABZ92175 XM_011516276 XP_011514578 NM_006193 NP_006184 |
| Function | Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity. |
| Subcellular Location | Nucleus. |
| Top Pathways | Maturity onset diabetes of the young |
paired box 4, ELISA Kit - MBS9332406 from MyBioSource
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Human PAX4 ELISA Kit - E028121 from Biobool
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anti-PAX4 antibody - ARG65216 from Arigo Biolaboratories
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