PAX4

Gene Symbol	PAX4
Entrez Gene	5078
Alt Symbol	KPD, MODY9
Species	Human
Gene Type	protein-coding
Description	paired box 4
Other Description	paired box gene 4|paired box protein Pax-4|paired domain gene 4
Swissprots	O95161 Q6B0H0 O43316
Accessions	EAL24318 EAW83633 EAW83634 O43316 AB008913 BAA24506 AF043978 AAD02289 BC074761 AAH74761 BC107149 AAI07150 BC107150 AAI07151 DQ442656 ABD97848 EU446646 ABZ92175 XM_011516276 XP_011514578 NM_006193 NP_006184
Function	Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Subcellular Location	Nucleus.
Top Pathways	Maturity onset diabetes of the young

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAX4-Over-expression-Lysate - LY12083a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PAX4 overexpression lysate - LY401865 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PAX4 293 Cell Lysate - 401661 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Pax4 Overexpression Lysate (Native) - NBL1-14130 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PAX4 Over-expression Lysate Product - GWB-76219D from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Pax4 Overexpression Lysate (Denatured) - H00005078-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human PAX4 Knockdown Stable Cell Line - CSC-DC011343 from Creative biogene Category Cell Line Species Human

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