PAX4

Gene Symbol PAX4
Entrez Gene 5078
Alt Symbol KPD, MODY9
Species Human
Gene Type protein-coding
Description paired box 4
Other Description paired box gene 4|paired box protein Pax-4|paired domain gene 4
Swissprots O95161 Q6B0H0 O43316
Accessions EAL24318 EAW83633 EAW83634 O43316 AB008913 BAA24506 AF043978 AAD02289 BC074761 AAH74761 BC107149 AAI07150 BC107150 AAI07151 DQ442656 ABD97848 EU446646 ABZ92175 XM_011516276 XP_011514578 NM_006193 NP_006184
Function Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Subcellular Location Nucleus.
Top Pathways Maturity onset diabetes of the young

Pax-4 CRISPR/Cas9 KO Plasmid (h) - sc-406061 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pax-4 HDR Plasmid (h) - sc-406061-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pax-4 Double Nickase Plasmid (h) - sc-406061-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pax-4 Double Nickase Plasmid (h2) - sc-406061-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pax-4 CRISPR Activation Plasmid (h) - sc-406061-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pax-4 CRISPR Activation Plasmid (h2) - sc-406061-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pax-4 Lentiviral Activation Particles (h) - sc-406061-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pax-4 Lentiviral Activation Particles (h2) - sc-406061-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pax-4 siRNA (h) - sc-43998 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pax-4 shRNA Plasmid (h) - sc-43998-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pax-4 shRNA (h) Lentiviral Particles - sc-43998-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pax4 RNAi - H00005078-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU122671 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16372 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16372 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06420 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06420

PAX4 siRNA (Human) - CRH3376 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PAX4 (NM_006193.2) - SHH371140 from Creative biogene

Category siRNA
Species Reactivities Human

Human PAX4 siRNA - orb263878 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PAX4 shRNA Plasmid (Human) - CHH3376 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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