NR5A1

Gene Symbol	NR5A1
Entrez Gene	2516
Alt Symbol	AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 5, group A, member 1
Other Description	STF-1|adrenal 4 binding protein|adrenal 4-binding protein|fushi tarazu factor homolog 1|nuclear receptor AdBP4|steroid hormone receptor Ad4BP|steroidogenic factor 1|steroidogenic factor 1 nuclear receptor|steroidogenic factor-1
Swissprots	O15196 Q13285 Q5T6F5
Accessions	AAA75332 AAS48621 BAA13546 BAB18655 CCQ43292 EAW87591 Q13285 AB307718 BAH02309 AK090858 BC032501 AAH32501 EU446475 ABZ92004 HQ692856 ADZ17367 HQ709184 ADZ17391 JF432187 ADZ15404 U76388 AAB53105 XM_005251871 XP_005251928 XM_005251872 XP_005251929 XM_011518455 XP_011516757 XM_011518456 XP_011516758 NM_004959 NP_004950
Function	Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO- NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phosphatidylcholine (By similarity). Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. {ECO:0000250, ECO:0000269|PubMed:17210646}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:11479297}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Steroidogenic Factor 1, SF1, Human, ELISA Kit - E-EL-H1352 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Steroidogenic Factor 1, Human, ELISA Kit - E01S0093 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Steroidogenic Factor 1, SF1, Mouse, ELISA Kit - E-EL-M1092 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Steroidogenic Factor 1, SF1, Rat, ELISA Kit - E-EL-R0920 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Steroidogenic Factor 1, SF1, Rabbit, ELISA Kit - E-EL-RB1995 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Steroidogenic Factor 1, SF1, Chicken, ELISA Kit - E-EL-Ch1430 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Steroidogenic Factor 1, SF1, Porcine, ELISA Kit - E-EL-P1258 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Steroidogenic Factor 1, SF1, Guinea Pig, ELISA Kit - E-EL-GP1153 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Steroidogenic Factor 1, SF1, Monkey, ELISA Kit - E-EL-MK1255 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Steroidogenic Factor 1, ELISA Kit - MBS750002 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS755122 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Steroidogenic Factor 1, ELISA Kit - MBS744885 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Steroidogenic Factor 1, ELISA Kit - MBS031159 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS023489 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic factor 1, ELISA Kit - MBS282825 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS093136 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS036823 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS075236 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS026597 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS044267 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS015868 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS046090 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/ml. Range 3.12 ng/ml - 100 ng/ml.

Steroidogenic Factor 1, ELISA Kit - MBS012811 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS008974 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Steroidogenic Factor 1, ELISA Kit - MBS014109 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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