Gene Symbol |
SYT4
|
Entrez Gene |
6860
|
Alt Symbol |
HsT1192
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
synaptotagmin IV
|
Other Description |
synaptotagmin 4|synaptotagmin-4|sytIV
|
Swissprots |
Q9H2B2 B4DEU3 Q9P2K4
|
Accessions |
EAX01433 EAX01434 Q9H2B2 AB037763 BAA92580 AF299075 AAG37229 AI912792 AK291154 BAF83843 AK293791 BAG57204 AK297275 BAG59747 AK297379 BAG59821 AK299593 BAG61525 AK299652 BAG61571 AK311335 AK311469 BC036538 AAH36538 BM311221 DB483932 EU176218 ABW03669 NM_020783 NP_065834
|
Function |
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
|
Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.
|
Tissue Specificity |
Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus.
|