Gene Symbol | SYT4 |
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Entrez Gene | 6860 |
Alt Symbol | HsT1192 |
Species | Human |
Gene Type | protein-coding |
Description | synaptotagmin IV |
Other Description | synaptotagmin 4|synaptotagmin-4|sytIV |
Swissprots | Q9H2B2 B4DEU3 Q9P2K4 |
Accessions | EAX01433 EAX01434 Q9H2B2 AB037763 BAA92580 AF299075 AAG37229 AI912792 AK291154 BAF83843 AK293791 BAG57204 AK297275 BAG59747 AK297379 BAG59821 AK299593 BAG61525 AK299652 BAG61571 AK311335 AK311469 BC036538 AAH36538 BM311221 DB483932 EU176218 ABW03669 NM_020783 NP_065834 |
Function | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. |
Tissue Specificity | Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus. |
Synaptotagmin IV CRISPR/Cas9 KO Plasmid (h) - sc-403314 from Santa Cruz Biotechnology
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Synaptotagmin IV HDR Plasmid (h) - sc-403314-HDR from Santa Cruz Biotechnology
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Synaptotagmin IV Double Nickase Plasmid (h) - sc-403314-NIC from Santa Cruz Biotechnology
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Synaptotagmin IV Double Nickase Plasmid (h2) - sc-403314-NIC-2 from Santa Cruz Biotechnology
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Synaptotagmin IV CRISPR Activation Plasmid (h) - sc-403314-ACT from Santa Cruz Biotechnology
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Synaptotagmin IV CRISPR Activation Plasmid (h2) - sc-403314-ACT-2 from Santa Cruz Biotechnology
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Synaptotagmin IV Lentiviral Activation Particles (h) - sc-403314-LAC from Santa Cruz Biotechnology
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Synaptotagmin IV Lentiviral Activation Particles (h2) - sc-403314-LAC-2 from Santa Cruz Biotechnology
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Synaptotagmin IV siRNA (h) - sc-41316 from Santa Cruz Biotechnology
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Synaptotagmin IV shRNA Plasmid (h) - sc-41316-SH from Santa Cruz Biotechnology
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Synaptotagmin IV shRNA (h) Lentiviral Particles - sc-41316-V from Santa Cruz Biotechnology
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Synaptotagmin 4 RNAi - H00006860-R01 from Novus Biologicals
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MISSION® esiRNA - EHU032901 from Sigma-Aldrich
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MISSION® esiRNA - EHU101351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20924 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20924 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11385 from Sigma-Aldrich
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SYT4 siRNA (Human) - CRH4690 from Cohesion Biosciences
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SYT4 - MBS8208943 from MyBioSource
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shRNA set against Human SYT4 (NM_020783.3) - SHH422044 from Creative biogene
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SYT4 shRNA Plasmid (Human) - CHH4690 from Cohesion Biosciences
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SYT4 miRNA 3'UTR clone - MiUTR4H-TG08711 from Creative biogene
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