Gene Symbol | SYT4 |
---|---|
Entrez Gene | 6860 |
Alt Symbol | HsT1192 |
Species | Human |
Gene Type | protein-coding |
Description | synaptotagmin IV |
Other Description | synaptotagmin 4|synaptotagmin-4|sytIV |
Swissprots | Q9H2B2 B4DEU3 Q9P2K4 |
Accessions | EAX01433 EAX01434 Q9H2B2 AB037763 BAA92580 AF299075 AAG37229 AI912792 AK291154 BAF83843 AK293791 BAG57204 AK297275 BAG59747 AK297379 BAG59821 AK299593 BAG61525 AK299652 BAG61571 AK311335 AK311469 BC036538 AAH36538 BM311221 DB483932 EU176218 ABW03669 NM_020783 NP_065834 |
Function | May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. |
Tissue Specificity | Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus. |