KDM6B

Gene Symbol KDM6B
Entrez Gene 23135
Alt Symbol JMJD3
Species Human
Gene Type protein-coding
Description lysine (K)-specific demethylase 6B
Other Description jmjC domain-containing protein 3|jumonji domain containing 3, histone lysine demethylase|jumonji domain-containing protein 3|lysine demethylase 6B|lysine-specific demethylase 6B
Swissprots O15054 Q96G33 C9IZ40
Accessions EAW90127 EAW90128 O15054 AB002344 BAA21572 BC009994 AAH09994 BC035897 XM_005256549 XP_005256606 XM_005256550 XP_005256607 XM_005256551 XP_005256608 XM_005256552 XP_005256609 XM_005256554 XP_005256611 XM_006721483 XP_006721546 XM_006721484 XP_006721547 XM_011523750 XP_011522052 XM_011523751 XP_011522053 XM_011523752 XP_011522054 XM_011523753 XP_011522055 XM_011523754 XP_011522056 NM_001080424 NP_001073893
Function Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. {ECO:0000269|PubMed:17825402, ECO:0000269|PubMed:17851529}.
Subcellular Location Nucleus {ECO:0000305|PubMed:17825402}.

JMJD3 CRISPR/Cas9 KO Plasmid (h) - sc-401883 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 HDR Plasmid (h) - sc-401883-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 Double Nickase Plasmid (h) - sc-401883-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 Double Nickase Plasmid (h2) - sc-401883-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 CRISPR Activation Plasmid (h) - sc-401883-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 CRISPR Activation Plasmid (h2) - sc-401883-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 Lentiviral Activation Particles (h) - sc-401883-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 Lentiviral Activation Particles (h2) - sc-401883-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 siRNA (h) - sc-93819 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD3 shRNA Plasmid (h) - sc-93819-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD3 shRNA (h) Lentiviral Particles - sc-93819-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU008271 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11039 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11039 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KDM6B siRNA (Human) - CRH8023 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

JMJD3 CRISPR/Cas9 KO Plasmid (h2) - sc-401883-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD3 HDR Plasmid (h2) - sc-401883-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human KDM6B (NM_001080424.1) - SHH324279 from Creative biogene

Category siRNA
Species Reactivities Human

KDM6B shRNA Plasmid (Human) - CHH8023 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KDM6B miRNA 3'UTR clone - MiUTR1H-05070 from Creative biogene

Species Reactivities Human
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