KDM6B

Gene Symbol	KDM6B
Entrez Gene	23135
Alt Symbol	JMJD3
Species	Human
Gene Type	protein-coding
Description	lysine (K)-specific demethylase 6B
Other Description	jmjC domain-containing protein 3|jumonji domain containing 3, histone lysine demethylase|jumonji domain-containing protein 3|lysine demethylase 6B|lysine-specific demethylase 6B
Swissprots	O15054 Q96G33 C9IZ40
Accessions	EAW90127 EAW90128 O15054 AB002344 BAA21572 BC009994 AAH09994 BC035897 XM_005256549 XP_005256606 XM_005256550 XP_005256607 XM_005256551 XP_005256608 XM_005256552 XP_005256609 XM_005256554 XP_005256611 XM_006721483 XP_006721546 XM_006721484 XP_006721547 XM_011523750 XP_011522052 XM_011523751 XP_011522053 XM_011523752 XP_011522054 XM_011523753 XP_011522055 XM_011523754 XP_011522056 NM_001080424 NP_001073893
Function	Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. {ECO:0000269|PubMed:17825402, ECO:0000269|PubMed:17851529}.
Subcellular Location	Nucleus {ECO:0000305|PubMed:17825402}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human KDM6B / JMJD3 protein fragment - ab196420 from Abcam Category Protein Prices $1,281.00 Sizes 20 µg Source Baculovirus infected sf9 cells Species Human

Human KDM6B / JMJD3 peptide - ab38111 from Abcam Category Peptide

Human KDM6B / JMJD3 peptide - ab38112 from Abcam Category Peptide

KDM6B / JMJD3 Antibody Blocking Peptide - LS-E121 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KDM6B / JMJD3 Antibody Blocking Peptide - LS-E122 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KDM6B / JMJD3 Blocking Peptide - LS-E123 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KDM6B / JMJD3 Blocking Peptide - LS-E5012 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KDM6B / JMJD3 Antibody Blocking Peptide - LS-E14585 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KDM6B / JMJD3 Antibody Blocking Peptide - LS-E31221 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Blocking Peptide - NBP1-06640PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Peptide - P0157 from Novus Biologicals Category Peptide Species Human

JMJD3-Antibody-N-term-Blocking-Peptide - BP1022a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KDM6B-Antibody-N-term-Blocking-Peptide - BP17413a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

JMJD3 Blocking Peptide - 33R-3834 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

JMJD3 Blocking Peptide - 33R-1207 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

JMJD3 / KDM6B (N-term) Control Peptide - AP55610CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

JMJD3 Peptide - 6657P from ProSci Category Peptide Species Human

Recombinant Human KDM6B - KDM6B-1066H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human KDM6B, Flag-tagged - KDM6B-562H from Creative Biomart Category Protein Source Insect cells Species Human

Recombinant Human Lysine-specific demethylase 6B(KDM6B) ,partial - CSB-YP517674HU CSB-EP517674HU CSB-BP517674HU CSB-MP517674HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

KDM6B-Blocking-Peptide-Center - BP21160a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KDM6B Peptide, Human - M34GP08055H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant JMJD3 / KDM6B (1043-1682) protein - 31519 from ActiveMotif Category Protein Prices $395.00, $3,500.00 Sizes 20 µg, 1 mg Source Baculovirus Species Human

Lysine-specific demethylase 6B (KDM6B), partial, Recombinant Protein - MBS1041665 from MyBioSource Category Protein Prices $930.00, $930.00, $1,155.00, $1,155.00, $1,330.00, $1,330.00, $1,790.00, $1,790.00, $1,825.00, $2,615.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

JMJD3 fusion protein - Ag26524 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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