HIBCH

Gene Symbol	HIBCH
Entrez Gene	26275
Alt Symbol	HIBYLCOAH
Species	Human
Gene Type	protein-coding
Description	3-hydroxyisobutyryl-CoA hydrolase
Other Description	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial|3-hydroxyisobutyryl-Coenzyme A hydrolase|HIB-CoA hydrolase|HIBYL-CoA-H
Swissprots	Q53RF7 Q53GF2 Q53GA8 Q53TC6 D3DPI4 Q6NVY1 Q92931 Q9BS94
Accessions	AAX93234 AAY24178 EAX10873 EAX10874 EAX10875 EAX10876 EAX10877 Q6NVY1 AI767349 AK126890 AK222979 BAD96699 AK223023 BAD96743 AK308042 AK313651 BC005190 AAH05190 BC067822 AAH67822 BI764401 BP193393 CA448468 CA453768 DB034438 U66669 AAC52114 XM_011510953 XP_011509255 XM_011510954 XP_011509256 XR_922903 NM_014362 NP_055177 NM_198047 NP_932164
Function	Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA. {ECO:0000269|PubMed:8824301}.
Subcellular Location	Mitochondrion {ECO:0000250}.
Tissue Specificity	Highly expressed in liver and kidney, also detected in heart, muscle and brain (at protein level). Not detected in lung. {ECO:0000269|PubMed:8824301}.
Top Pathways	Carbon metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HIBCH full length protein - ab124585 from Abcam Category Protein Source E. coli Species Human

Human HIBCH protein fragment - ab127345 from Abcam Category Protein Source E. coli Species Human

HIBCH Antibody Blocking Peptide - LS-E8950 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HIBCH Recombinant Protein - H00026275-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human HIBCH Protein - NBP1-99055 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E. coli Species Human

HIBCH-Antibody-Center-Blocking-Peptide - BP7435c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HIBCH Protein - GTX109167-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Human HIBCH protein - orb168496 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

HIBCH protein (His tag) - 80R-2212 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

HIBCH (33-386, His-tag) - AR50294PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

HIBCH (33-386, His-tag) - AR50294PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

HIBCH - H00026275-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

HIBCH, 33-386 aa, Human, His tag, E.coli - 01-P1469 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

HIBCH fusion protein - Ag6473 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

HIBCH fusion protein - Ag6149 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

HIBCH Human - ENPS-601 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source E.coli. Species Human

Recombinant Human 3-Hydroxyisobutyryl-CoA Hydrolase Enzyme - BP002548-ENZ-594 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

HIBCH, 33-386 aa, Recombinant Protein - GWB-P0569J from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human HIBCH, His-tagged - HIBCH-13772H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial(HIBCH) - CSB-YP747360HU CSB-EP747360HU CSB-BP747360HU CSB-MP747360HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HIBCH, 33-386aa, Human, His tag, E.coli - ATGP1469 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 10 µg, 50 µg, 250 µg Species Human

3-Hydroxyisobutyryl-CoA Hydrolase, Recombinant Protein - MBS144549 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH), Recombinant Protein - MBS1414743 from MyBioSource Category Protein Prices $1,120.00, $1,120.00, $1,350.00, $1,350.00, $1,775.00, $1,775.00, $2,240.00, $2,240.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

3-Hydroxyisobutyryl-CoA Hydrolase (Recombinant) - abx073796 from Abbexa

HIBCH (transcript variant 1) - TP309814 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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