KIF2A

Gene Symbol KIF2A
Entrez Gene 3796
Alt Symbol CDCBM3, HK2, KIF2
Species Human
Gene Type protein-coding
Description kinesin heavy chain member 2A
Other Description Kinesin, heavy chain, 2|kinesin-2|kinesin-like protein KIF2A
Swissprots Q8N5Q7 D3DW97 Q7Z5I3 A5YM54 E9PB70 B4DY54 A5YM42 O00139
Accessions EAW51387 EAW51388 EAW51389 EAW51390 O00139 AI652174 AK297347 BAG59797 AK302270 BAG63616 AK307880 AK315866 BAF98757 AY317140 AAP84320 AY429552 BC031828 AAH31828 BC047544 DB452624 DB456309 DQ891347 ABM82273 DQ894527 ABM85453 EF560716 ABQ59026 EF560728 ABQ59038 EU832810 ACE87821 GQ129246 ACT64380 Y08319 CAA69621 NM_001098511 NP_001091981 NM_001243952 NP_001230881 NM_001243953 NP_001230882 NM_004520 NP_004511
Function Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. {ECO:0000269|PubMed:15843429, ECO:0000269|PubMed:17538014, ECO:0000269|PubMed:18411309}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.

KIF2A (D-7) - sc-271471 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KIF2A (D-7): sc-271471. Western blot analysis of KIF2A expression in non-transfected: sc-117752 (A) and mouse KIF2A transfected: sc-121213 (B) 293T whole cell lysates.

KIF2A (D-7) - sc-398010 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KIF2A (D-7): sc-398010. Western blot analysis of KIF2A expression in SK-N-MC (A), T98G (B) and H4 (C) whole cell lysates.

KIF2A (C-20) - sc-48230 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KIF2A (C-20): sc-48230. Western blot analysis of KIF2A expression in non-transfected: sc-117752 (A) and mouse KIF2A transfected: sc-121213 (B) 293T whole cell lysates.

KIF2A (F-2) - sc-271027 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KIF2A (F-2): sc-271027. Western blot analysis of KIF2A expression in non-transfected: sc-117752 (A) and mouse KIF2A transfected: sc-121213 (B) 293T whole cell lysates.

KIF2A (G-11) - sc-271005 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KIF2A (G-11): sc-271005. Western blot analysis of KIF2A expression in non-transfected: sc-117752 (A) and mouse KIF2A transfected: sc-121213 (B) 293T whole cell lysates.

KIF2A (H-115) - sc-99122 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KIF2A (H-115): sc-99122. Western blot analysis of KIF2A expression in HeLa (A) and NIH/3T3 (B) whole cell lysates.

KIF2A (7) - sc-136396 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KIF2A (7): sc-136396. Western blot analysis of KIF2A expression in rat brain tissue extract.

KIF2A (N-14) - sc-48231 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KIF2A (N-14): sc-48231. Western blot analysis of KIF2A expression in mouse brain tissue extract.

Anti-Kif2a antibody - ab197988 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Kif2a antibody (ab197988) at 1/350 dilution + HeLa cell lysate at 40 µg

Anti-Kif2a antibody - ab86655 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Kif2a antibody (ab86655) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 5 : NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell LysateLane 6 : MEF1 (Mouse embryonic fibroblast cell line) Whole Cell LysateLane 7 : F9 (Mouse embryonic carcinoma cell line) Whole Cell LysateLane 8 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate with Immunizing peptide at 1 µg/mlLane 9 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate with Immunizing peptide at 1 µg/mlLane 10 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate with Immunizing peptide at 1 µg/mlLane 11 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate with Immunizing peptide at 1 µg/mlLane 12

Anti-Kif2a antibody - ab3475 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Kif2a antibody - ab55383 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Kif2a antibody (ab55383) used in immunohistochemistry at 6ug/ml on formalin fixed and paraffin embedded human testis.

Anti-Kif2a antibody - ab80492 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Kif2a antibody (ab80492) at 1 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 - 1/100000

Anti-Kif2a antibody - ab71160 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Kif2a antibody (ab71160) at 0.04 µg/mlLane 1 : Whole cell lysate from Hela cells at 50 µgLane 2 : Whole cell lysate from Hela cells at 15 µgLane 3 : Whole cell lysate from Hela cells at 5 µgLane 4 : Whole cell lysate from 293T cells at 50 µgLane 5 : Whole cell lysate from NIH3T3 cells at 50 µg

Anti-Kif2a antibody - ab37005 from Abcam

Prices $394.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab37005, at a 1/5000 dilution, staining HeLa cells fixed in 3.5% paraformaldehyde, by immunofluorescence. Centrosome staining during interphase and spindle pole staining during mitosis.

Anti-Kinesin Heavy Chain 2 antibody [EPR10740(B)] - ab154868 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10740(B)
Immunofluorescent analysis of Jurkat cells labeling Kinesin Heavy Chain 2 with ab154868 at 1/100.

Anti-KIF2A Antibody (N-Terminus) - LS-C71341 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KIF2A Antibody (aa100-150) - LS-C287751 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KIF2A Antibody (aa630-679) - LS-C287752 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KIF2A / Kinesin-2 Antibody (aa1-680, Azide-free) - LS-C330499 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-KIF2A Antibody (aa578-627) - LS-C80081 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-KIF2A Antibody (C-Terminus) - LS-C109842 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KIF2A antibody LS-C109842 Western blot of 721_B cell lysate.

Anti-KIF2A Antibody (clone 2D4) - LS-C133278 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D4
Detection limit for recombinant GST tagged KIF2 is approximately 0.1 ng/ml as a capture antibody.

Anti-KIF2A Antibody (N-Terminus) IHC-plus™ - LS-B251 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KIF2A antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B251 dilution 1:500.

Anti-KIF2A Antibody (aa72-121) IHC-plus™ - LS-B6538 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KIF2A antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6538 concentration 5 ug/ml.
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