KIF2A

Gene Symbol KIF2A
Entrez Gene 3796
Alt Symbol CDCBM3, HK2, KIF2
Species Human
Gene Type protein-coding
Description kinesin heavy chain member 2A
Other Description Kinesin, heavy chain, 2|kinesin-2|kinesin-like protein KIF2A
Swissprots Q8N5Q7 D3DW97 Q7Z5I3 A5YM54 E9PB70 B4DY54 A5YM42 O00139
Accessions EAW51387 EAW51388 EAW51389 EAW51390 O00139 AI652174 AK297347 BAG59797 AK302270 BAG63616 AK307880 AK315866 BAF98757 AY317140 AAP84320 AY429552 BC031828 AAH31828 BC047544 DB452624 DB456309 DQ891347 ABM82273 DQ894527 ABM85453 EF560716 ABQ59026 EF560728 ABQ59038 EU832810 ACE87821 GQ129246 ACT64380 Y08319 CAA69621 NM_001098511 NP_001091981 NM_001243952 NP_001230881 NM_001243953 NP_001230882 NM_004520 NP_004511
Function Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. {ECO:0000269|PubMed:15843429, ECO:0000269|PubMed:17538014, ECO:0000269|PubMed:18411309}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.

KIF2A CRISPR/Cas9 KO Plasmid (h) - sc-405146 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIF2A HDR Plasmid (h) - sc-405146-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIF2A Double Nickase Plasmid (h) - sc-405146-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIF2A Double Nickase Plasmid (h2) - sc-405146-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIF2A CRISPR Activation Plasmid (h) - sc-405146-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIF2A CRISPR Activation Plasmid (h2) - sc-405146-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIF2A Lentiviral Activation Particles (h) - sc-405146-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIF2A Lentiviral Activation Particles (h2) - sc-405146-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIF2A siRNA (h) - sc-60884 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIF2A shRNA Plasmid (h) - sc-60884-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIF2A shRNA (h) Lentiviral Particles - sc-60884-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU042151 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11196 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11196 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06489 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06489

KIF2A siRNA (Human) - CRH2567 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Kif2a RNAi - H00003796-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Kif2a RNAi - H00003796-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human KIF2A (NM_004520.4) - SHH325247 from Creative biogene

Category siRNA
Species Reactivities Human

Human KIF2A siRNA - orb263069 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KIF2A shRNA Plasmid (Human) - CHH2567 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KIF2A miRNA 3'UTR clone - MiUTR3H-05109 from Creative biogene

Species Reactivities Human

KIF2A miRNA 3'UTR clone - MiUTR3H-05110 from Creative biogene

Species Reactivities Human
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