NFX1

Gene Symbol NFX1
Entrez Gene 4799
Alt Symbol NFX2, TEG-42, Tex42
Species Human
Gene Type protein-coding
Description nuclear transcription factor, X-box binding 1
Other Description nuclear transcription factor, X box-binding protein 1|transcriptional repressor NF-X1
Swissprots Q9BXI1 Q96EL5 Q12986 Q5VXW6 A8K6H8
Accessions AAB94787 EAW58507 EAW58508 EAW58509 EAW58510 EAW58511 Q12986 AF332009 AAK16545 AI679589 AK055847 AK225750 AK291643 BAF84332 AL832342 AW674001 BC006447 AAH06447 BC012151 AAH12151 BP871782 BX647337 DA093124 DQ893676 ABM84602 DQ895843 ABM86769 U15306 AAA69517 XM_005251473 XP_005251530 XM_005251474 XP_005251531 XM_005251475 XP_005251532 NM_002504 NP_002495 NM_147133 NP_667344 NM_147134 NP_667345
Function Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination. {ECO:0000269|PubMed:10500182, ECO:0000269|PubMed:15371341, ECO:0000269|PubMed:17267499}.
Subcellular Location Nucleus.

Human NFX1 protein fragment - ab158994 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158994 on a 12.5% SDS-PAGE stained with Coomassie Blue.

NFX1 Antibody Blocking Peptide - LS-E10797 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NFX1 Antibody Blocking Peptide - LS-E12386 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human NFX1 Protein - H00004799-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

NFX1 - H00004799-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

NFX1 - H00004799-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

NFX1 fusion protein - Ag9474 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

NFX1 fusion protein - Ag9448 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human NFX1, His-tagged - NFX1-1284H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Transcriptional repressor NF-X1(NFX1) ,partial - CSB-YP621527HU CSB-EP621527HU CSB-BP621527HU CSB-MP621527HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

NFX1 Peptide, Human - M34GP10352H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

NFX1 Recombinant Protein Antigen - NBP2-57148PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

NFX1 Recombinant Protein Antigen - NBP2-58058PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

NFX1 Recombinant Protein Antigen - NBP2-57963PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
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