Gene Symbol | RABEP1 |
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Entrez Gene | 9135 |
Alt Symbol | RAB5EP, RABPT5 |
Species | Human |
Gene Type | protein-coding |
Description | rabaptin, RAB GTPase binding effector protein 1 |
Other Description | neurocrescin|rab GTPase-binding effector protein 1|rabaptin-4|rabaptin-5|rabaptin-5alpha|renal carcinoma antigen NY-REN-17 |
Swissprots | O95369 Q8IVX3 Q15276 B2RAG7 |
Accessions | EAW90343 EAW90344 EAW90345 Q15276 AA873800 AF098638 AAC70781 AK297535 BAG59936 AK310932 AK314183 BAG36864 AL050211 AL120839 AL157499 BC018742 BC032435 AAH32435 BC041700 AAH41700 BC065242 BI666786 BM678290 BX103338 DB124187 DB169027 EB387308 X77723 X91141 CAA62580 XM_011524060 XP_011522362 XM_011524061 XP_011522363 NM_001083585 NP_001077054 NM_001291581 NP_001278510 NM_001291582 NP_001278511 NM_004703 NP_004694 |
Function | Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. {ECO:0000269|PubMed:10698684, ECO:0000269|PubMed:11452015, ECO:0000269|PubMed:12773381, ECO:0000269|PubMed:22841712, ECO:0000269|PubMed:8521472}. |
Subcellular Location | Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle. |
Top Pathways | Endocytosis |
RABAPTIN-5 (B-8) - sc-271069 from Santa Cruz Biotechnology
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RABAPTIN-5 (D-11) - sc-46658 from Santa Cruz Biotechnology
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RABAPTIN-5 (G-9) - sc-25275 from Santa Cruz Biotechnology
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RABAPTIN-5 (H-300) - sc-15351 from Santa Cruz Biotechnology
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RABAPTIN-5 (C-20) - sc-6162 from Santa Cruz Biotechnology
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RABAPTIN-5 (20) - sc-136051 from Santa Cruz Biotechnology
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Anti-RABEP1 antibody - ab111199 from Abcam
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Anti-RABEP1 antibody - N-terminal - ab187725 from Abcam
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Anti-RABEP1 / Rabaptin-5 Antibody (aa300-350) - LS-C289532 from LifeSpan Bioscience
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Anti-RABEP1 / Rabaptin-5 Antibody (aa812-862) - LS-C289533 from LifeSpan Bioscience
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Anti-RABEP1 / Rabaptin-5 Antibody (aa549-598) - LS-C120282 from LifeSpan Bioscience
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RABEP1 Antibody - NBP1-82588 from Novus Biologicals
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RABEP1 Antibody - NBP1-82590 from Novus Biologicals
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RABEP1 Antibody - NBP1-82589 from Novus Biologicals
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RABEP1 Antibody - NBP1-47285 from Novus Biologicals
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RABEP1 Antibody (3H6) - H00009135-M06 from Novus Biologicals
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Monoclonal Anti-RABEP1, (C-terminal) antibody produced in mouse - SAB1402451 from Sigma-Aldrich
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Anti-RABEP1 antibody produced in rabbit - HPA024235 from Sigma-Aldrich
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Anti-RABEP1 antibody produced in rabbit - SAB4503558 from Sigma-Aldrich
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Anti-RABEP1 antibody produced in rabbit - HPA024691 from Sigma-Aldrich
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Anti-RABEP1 antibody produced in rabbit - HPA019669 from Sigma-Aldrich
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RABEP1-Antibody-Center - AP21346c from Abgent, a WuXi AppTec company
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RABEP1 Antibody (OAAF04107) - OAAF04107 from Aviva Systems Biology
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RABEP1 Polyclonal Antibody - A4273 from ABclonal
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RABEP1 antibody - 70R-19729 from Fitzgerald
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