Gene Symbol | RABEP1 |
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Entrez Gene | 9135 |
Alt Symbol | RAB5EP, RABPT5 |
Species | Human |
Gene Type | protein-coding |
Description | rabaptin, RAB GTPase binding effector protein 1 |
Other Description | neurocrescin|rab GTPase-binding effector protein 1|rabaptin-4|rabaptin-5|rabaptin-5alpha|renal carcinoma antigen NY-REN-17 |
Swissprots | O95369 Q8IVX3 Q15276 B2RAG7 |
Accessions | EAW90343 EAW90344 EAW90345 Q15276 AA873800 AF098638 AAC70781 AK297535 BAG59936 AK310932 AK314183 BAG36864 AL050211 AL120839 AL157499 BC018742 BC032435 AAH32435 BC041700 AAH41700 BC065242 BI666786 BM678290 BX103338 DB124187 DB169027 EB387308 X77723 X91141 CAA62580 XM_011524060 XP_011522362 XM_011524061 XP_011522363 NM_001083585 NP_001077054 NM_001291581 NP_001278510 NM_001291582 NP_001278511 NM_004703 NP_004694 |
Function | Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. {ECO:0000269|PubMed:10698684, ECO:0000269|PubMed:11452015, ECO:0000269|PubMed:12773381, ECO:0000269|PubMed:22841712, ECO:0000269|PubMed:8521472}. |
Subcellular Location | Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle. |
Top Pathways | Endocytosis |
Human RABEP1 protein fragment - ab160352 from Abcam
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Recombinant Human RABEP1 Protein - H00009135-Q01 from Novus Biologicals
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RABEP1 - H00009135-Q01-10 from Acris Antibodies
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RABEP1 - H00009135-Q01-25 from Acris Antibodies
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RABEP1 fusion protein - ag5693 from Proteintech Group
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RABEP1 fusion protein - ag6023 from Proteintech Group
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Recombinant Human Rab GTPase-binding effector protein 1(RABEP1) ,partial - CSB-YP614886HU CSB-EP614886HU CSB-BP614886HU CSB-MP614886HU from Cusabio
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RABAPTIN-5 (511-810) - sc-4346 WB from Santa Cruz Biotechnology
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RABEP1 (transcript variant 1) - TP308056 from Acris Antibodies
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RABEP1 Recombinant Protein Antigen - NBP1-82590PEP from Novus Biologicals
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RABEP1 Recombinant Protein Antigen - NBP1-82589PEP from Novus Biologicals
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RABEP1 Recombinant Protein Antigen - NBP1-82588PEP from Novus Biologicals
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RABEP1-Blocking-Peptide-Center - BP21346c from Abgent, a WuXi AppTec company
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RABEP1 Peptide, Human - M34GP12885H from Creative Peptides
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Rab GTPase-binding effector protein 1 (RABEP1), partial, Recombinant Protein - MBS1419962 from MyBioSource
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Recombinant Human RABEP1 Protein, MYC/DDK-tagged - RABEP1-299H from Creative Biomart
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