PLA2G15

Gene Symbol PLA2G15
Entrez Gene 23659
Alt Symbol ACS, GXVPLA2, LLPL, LPLA2, LYPLA3
Species Human
Gene Type protein-coding
Description phospholipase A2, group XV
Other Description 1-O-acylceramide synthase|LCAT-like lysophospholipase|group XV phospholipase A2|lysophospholipase 3 (lysosomal phospholipase A2)|lysosomal phospholipase A2
Swissprots Q9Y2B3 Q53GZ1 B3KMF3 Q9NPQ6 B4DUD1 Q8NCC3 Q9UG04
Accessions EAW83217 EAW83218 Q8NCC3 AB017494 BAA76877 AK001705 BAG50965 AK074828 BAC11233 AK127898 AK222790 BAD96510 AK296263 BAG58976 AK298494 BAG60702 AK300596 BAG62293 AL110209 CAB53675 AL389957 CAB97531 AY358425 AAQ88791 BC011640 AAH11640 BC062605 AAH62605 EU832326 ACE87583 XM_005255886 XP_005255943 XM_011522979 XP_011521281 XM_011522980 XP_011521282 NM_012320 NP_036452
Function Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N- acetylsphingosine and the concomitant release of a lyso- phospholipid (By similarity). May have weak lysophospholipase activity. {ECO:0000250}.
Subcellular Location Lysosome {ECO:0000250}. Secreted {ECO:0000269|PubMed:10092508}.
Tissue Specificity Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:10092508}.
Top Pathways Lysosome, Glycerophospholipid metabolism

LYPLA3 (H-167) - sc-135297 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LYPLA3 (H-167): sc-135297. Western blot analysis of LYPLA3 expression in HeLa (A) and K-562 (B) whole cell lysates.

LYPLA3 (G-14) - sc-164941 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LYPLA3 (B-2) - sc-376078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LYPLA3 (B-2): sc-376078. Western blot analysis of LYPLA3 expression in HeLa (A) and K-562 (B) whole cell lysates.

LYPLA3 (T-14) - sc-164943 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LYPLA3 (T-14): sc-164943. Western blot analysis of LYPLA3 expression in mouse heart (A) and mouse skeletal muscle (B) tissue extracts.

Anti-LYPLA3 antibody - ab154012 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LYPLA3 antibody (ab154012) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-LYPLA3 antibody - ab57004 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PLA2G15 / ACS Antibody - LS-C308843 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-PLA2G15 / ACS Antibody (aa314-413) - LS-C308846 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PLA2G15 / ACS Antibody - LS-C310911 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLA2G15 / ACS Antibody - LS-C310912 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G15 / ACS Antibody (aa314-413, Azide-free) - LS-C327786 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

LYPLA3 Antibody (3B11) - H00023659-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B11
Western Blot: LYPLA3 Antibody (3B11) [H00023659-M01] - LYPLA3 monoclonal antibody (M01), clone 3B11. Analysis of LYPLA3 expression in NIH/3T3.

LYPLA3 Antibody - NBP1-92088 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LYPLA3 Antibody [NBP1-92088] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

LYPLA3 Antibody - NBP2-17193 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LYPLA3 Antibody [NBP2-17193] - Sample (30 ug of whole cell lysate) A: Jurkat 10% SDS PAGE gel, diluted at 1:2000.

LYPLA3 Antibody - NBP1-92089 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LYPLA3 Antibody [NBP1-92089] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

LYPLA3 Antibody - NBP2-17192 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LYPLA3 Antibody [NBP2-17192] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE gel, diluted at 1:1000.

LYPLA3 Antibody - H00023659-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: LYPLA3 Antibody [H00023659-D01P] - Analysis of PLA2G15 expression in transfected 293T cell line by PLA2G15 polyclonal antibody.Lane 1: LYPLA3 transfected lysate(46.70 KDa).Lane 2: Non-transfected lysate.

LYPLA3 Antibody - H00023659-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: LYPLA3 Antibody [H00023659-B01P] - Analysis of PLA2G15 expression in transfected 293T cell line by PLA2G15 polyclonal antibody. Lane 1: LYPLA3 transfected lysate(45.32 KDa). Lane 2: Non-transfected lysate.

LYPLA3 Antibody - H00023659-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

LYPLA3 Antibody - H00023659-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-LYPLA3 antibody produced in mouse - WH0023659M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B11
<B>Immunoblotting</B><BR/>Monoclonal Anti-LYPLA3, <B>Cat. No. WH0023659M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~46.6 kDa using HeLa lysate.

Anti-PLA2G15 antibody produced in mouse - SAB1401599 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-PLA2G15, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401599</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~45.32 kDa using PLA2G15 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PLA2G15 antibody produced in rabbit - HPA041727 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PLA2G15: <B>Cat. No. HPA041727</B>: Immunohistochemical staining of human thyroid gland shows moderate cytoplasmic, nuclear and membranous positivity in glandular cells.

Anti-PLA2G15 antibody produced in rabbit - HPA041702 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PLA2G15: <B>Cat. No. HPA041702</B>: Immunohistochemical staining of human kidney shows cytoplasmic and nuclear positivity in tubular cells.

Anti-LYPLA3 antibody produced in rabbit - SAB1410441 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LYPLA3: <B>Cat. No. SAB1410441</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~46.7 kDa using PLA2G15 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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