PLA2G15

Gene Symbol PLA2G15
Entrez Gene 23659
Alt Symbol ACS, GXVPLA2, LLPL, LPLA2, LYPLA3
Species Human
Gene Type protein-coding
Description phospholipase A2, group XV
Other Description 1-O-acylceramide synthase|LCAT-like lysophospholipase|group XV phospholipase A2|lysophospholipase 3 (lysosomal phospholipase A2)|lysosomal phospholipase A2
Swissprots Q9Y2B3 Q53GZ1 B3KMF3 Q9NPQ6 B4DUD1 Q8NCC3 Q9UG04
Accessions EAW83217 EAW83218 Q8NCC3 AB017494 BAA76877 AK001705 BAG50965 AK074828 BAC11233 AK127898 AK222790 BAD96510 AK296263 BAG58976 AK298494 BAG60702 AK300596 BAG62293 AL110209 CAB53675 AL389957 CAB97531 AY358425 AAQ88791 BC011640 AAH11640 BC062605 AAH62605 EU832326 ACE87583 XM_005255886 XP_005255943 XM_011522979 XP_011521281 XM_011522980 XP_011521282 NM_012320 NP_036452
Function Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N- acetylsphingosine and the concomitant release of a lyso- phospholipid (By similarity). May have weak lysophospholipase activity. {ECO:0000250}.
Subcellular Location Lysosome {ECO:0000250}. Secreted {ECO:0000269|PubMed:10092508}.
Tissue Specificity Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:10092508}.
Top Pathways Lysosome, Glycerophospholipid metabolism

LYPLA3 CRISPR/Cas9 KO Plasmid (h) - sc-409535 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA3 HDR Plasmid (h) - sc-409535-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA3 Double Nickase Plasmid (h) - sc-409535-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA3 Double Nickase Plasmid (h2) - sc-409535-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA3 CRISPR Activation Plasmid (h) - sc-409535-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA3 CRISPR Activation Plasmid (h2) - sc-409535-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA3 Lentiviral Activation Particles (h) - sc-409535-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA3 Lentiviral Activation Particles (h2) - sc-409535-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA3 siRNA (h) - sc-93270 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYPLA3 shRNA Plasmid (h) - sc-93270-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYPLA3 shRNA (h) Lentiviral Particles - sc-93270-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYPLA3 RNAi - H00023659-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU149791 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16885 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16885 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09211 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09211

PLA2G15 siRNA (Human) - CRH8428 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLA2G15 (NM_012320.3) - SHH376700 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LYPLA3(NM_012320.3) - SHH168617 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLA2G15 siRNA - orb268930 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLA2G15 shRNA Plasmid (Human) - CHH8428 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLA2G15 miRNA 3'UTR clone - MiUTR1H-05978 from Creative biogene

Species Reactivities Human
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