RTCA

Gene Symbol	RTCA
Entrez Gene	8634
Alt Symbol	RPC, RTC1, RTCD1
Species	Human
Gene Type	protein-coding
Description	RNA 3'-terminal phosphate cyclase
Other Description	RNA terminal phosphate cyclase domain 1|RNA terminal phosphate cyclase domain-containing protein 1|RTC domain-containing protein 1
Swissprots	Q5VVL6 Q96E99 Q5VVL5 O00442
Accessions	CAA72365 EAW72961 EAW72962 O00442 AI587400 AK292366 BAF85055 AK299793 BAG61672 AK307445 AK309394 AU310497 BC012604 AAH12604 CA437545 CF141820 DA361597 DB576272 JF432517 ADZ15734 Y11651 CAA72364 XM_005271298 XP_005271355 XM_005271299 XP_005271356 NM_001130841 NP_001124313 NM_003729 NP_003720
Function	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
Subcellular Location	Nucleus, nucleoplasm.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RTCD1 full length protein - ab160126 from Abcam Category Protein Source Wheat germ Species Human

Human RTCD1 full length protein - ab181893 from Abcam Category Protein Source E. coli Species Human

RTCD1 / RPC Antibody Blocking Peptide - LS-E14774 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RTCD1 / RPC Antibody Blocking Peptide - LS-E14775 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RTCD1 Protein - H00008634-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RTCA peptide - orb218166 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

RTCA protein (His tag) - 80R-3868 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

RTCD1 Blocking Peptide - 33R-9747 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RPC Blocking Peptide - abx063497 from Abbexa Category Peptide Species Human, Mouse, Rat

RTCD1 (1-366, His-tag) - AR51555PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

RTCD1 (1-366, His-tag) - AR51555PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

RTCD1 - H00008634-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RTCD1 - H00008634-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RTCA, 1-366aa, Human, His tag, E.coli - 01-P2735 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

RTCD1 fusion protein - Ag9304 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

RTCD1 fusion protein - Ag8904 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RPC Blocking Peptide - CBP2303 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

RTCD1 Peptide - BS5918P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human RNA 3'-terminal phosphate cyclase(RTCD1) - CSB-YP520755HU CSB-EP520755HU CSB-BP520755HU CSB-MP520755HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RTCA, 1-366aa, Human, His tag, E.coli - ATGP2735 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 4 µg, 20 µg, 100 µg Species Human

RNA 3'-Terminal Phosphate Cyclase Protein (Recombinant) - abx263426 from Abbexa Category Protein

RTCD1 Recombinant Protein Antigen - NBP1-87113PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RTCD1 Recombinant Protein Antigen - NBP1-87112PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Human RTCA protein - orb260076 from Biorbyt Category Protein Prices $170.00, $289.00, $1,122.00 Sizes 2 μg, 10 μg, 100 μg Species Human

RTCD1-Antibody-C-term-Blocking-Peptide - BP6952b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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