RTCA

Gene Symbol RTCA
Entrez Gene 8634
Alt Symbol RPC, RTC1, RTCD1
Species Human
Gene Type protein-coding
Description RNA 3'-terminal phosphate cyclase
Other Description RNA terminal phosphate cyclase domain 1|RNA terminal phosphate cyclase domain-containing protein 1|RTC domain-containing protein 1
Swissprots Q5VVL6 Q96E99 Q5VVL5 O00442
Accessions CAA72365 EAW72961 EAW72962 O00442 AI587400 AK292366 BAF85055 AK299793 BAG61672 AK307445 AK309394 AU310497 BC012604 AAH12604 CA437545 CF141820 DA361597 DB576272 JF432517 ADZ15734 Y11651 CAA72364 XM_005271298 XP_005271355 XM_005271299 XP_005271356 NM_001130841 NP_001124313 NM_003729 NP_003720
Function Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
Subcellular Location Nucleus, nucleoplasm.
Tissue Specificity Ubiquitous.

RTCD1 CRISPR/Cas9 KO Plasmid (h) - sc-411197 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RTCD1 HDR Plasmid (h) - sc-411197-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RTCD1 Double Nickase Plasmid (h) - sc-411197-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RTCD1 Double Nickase Plasmid (h2) - sc-411197-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RTCD1 CRISPR Activation Plasmid (h) - sc-411197-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RTCD1 CRISPR Activation Plasmid (h2) - sc-411197-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RTCD1 Lentiviral Activation Particles (h) - sc-411197-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RTCD1 Lentiviral Activation Particles (h2) - sc-411197-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RTCD1 siRNA (h) - sc-88222 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RTCD1 shRNA Plasmid (h) - sc-88222-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RTCD1 shRNA (h) Lentiviral Particles - sc-88222-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RTCD1 RNAi - H00008634-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU093511 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18727 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18727 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02465 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02465

RTCA siRNA (Human) - CRH5673 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RTCA - MBS8222507 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RTCD1 (NM_003729.3) - SHH400428 from Creative biogene

Category siRNA
Species Reactivities Human

Human RTCA siRNA - orb266175 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RTCA shRNA Plasmid (Human) - CHH5673 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RTCA miRNA 3'UTR clone - MiUTR3H-11773 from Creative biogene

Species Reactivities Human

RTCA miRNA 3'UTR clone - MiUTR3H-11774 from Creative biogene

Species Reactivities Human
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