GRB7

Gene Symbol	GRB7
Entrez Gene	2886
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	growth factor receptor-bound protein 7
Other Description	B47|GRB7 adapter protein|epidermal growth factor receptor GRB-7
Swissprots	Q92568 Q53YD3 B3KNL0 B7WP75 B3KWP9 J3KQM4 Q14451 B2RAV1 Q96DF9 Q9Y220
Accessions	AAG25938 EAW60600 EAW60601 Q14451 AB008789 BAA29059 AB008790 BAA29060 AK027729 BAG51372 AK125544 BAG54211 AK222849 BAD96569 AK222870 BAD96590 AK290115 BAF82804 AK294620 BAG57803 AK314368 BAG36998 AU124875 BC006535 AAH06535 BE247550 BT006686 AAP35332 D43772 BAA07827 D87513 BAA13412 DC384178 DQ893861 ABM84787 EU176171 ABW03622 XM_011524683 XP_011522985 NM_001030002 NP_001025173 NM_001242442 NP_001229371 NM_001242443 NP_001229372 NM_005310 NP_005301
Function	Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic granule {ECO:0000250}. Cell projection. Note=Predominantly cytoplasmic. Detected in stress granules, where mRNA is stored under stress conditions (By similarity). {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GRB7 full length protein - ab116903 from Abcam Category Protein Source Wheat germ Species Human

Human GRB7 full length protein - ab125569 from Abcam Category Protein Source E. coli Species Human

Human GRB7 peptide - ab22920 from Abcam Category Peptide Species Human

Human GRB7 peptide - ab23170 from Abcam Category Peptide Species Human

GRB7 Antibody Blocking Peptide - LS-E25346 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRB7 Antibody Blocking Peptide - LS-E10146 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GRB7 Protein - H00002886-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human GRB7 Protein - H00002886-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GRB7-Antibody-Center-Blocking-Peptide - BP9469c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GRB7 (N Terminus) blocking peptide - GTX89926-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

GRB7 Immunizing peptide - orb17432 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

Human Grb7 Protein - abx066955 from Abbexa Category Protein Source E.coli Species Human

GRB7 Peptide - AC21-0174-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GRB7 - H00002886-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GRB7 - H00002886-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GRB7 - H00002886-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

GRB7 - H00002886-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Growth Factor Receptor Bound Protein 7 (Grb7), Human - 20-9077 from ARP American Research Products Category Protein Prices $527.00 Sizes 50 µg Source E.coli Species Human

GRB7 Peptide - 45-707P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

GRB7 fusion protein - Ag8646 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

GRB7 fusion protein - ag8537 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GRB7 fusion protein - ag0023 from Proteintech Group Category Protein Source E. coli-derived, Species Human

Recombinant Human Growth Factor Receptor-Bound Protein 7, GST-tagged - GRB7-4848H from Creative Biomart Category Protein Species Human

Recombinant Human GRB7 - GRB7-27926TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human GRB7, GST-tagged - GRB7-6971H from Creative Biomart Category Protein Source E. coli Species Human

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