IQGAP1

Gene Symbol IQGAP1
Entrez Gene 8826
Alt Symbol HUMORFA01, SAR1, p195
Species Human
Gene Type protein-coding
Description IQ motif containing GTPase activating protein 1
Other Description RasGAP-like with IQ motifs|ras GTPase-activating-like protein IQGAP1
Swissprots P46940 A7MBM3
Accessions EAX02102 EAX02103 P46940 AF401205 AAL02166 AI924000 AK055054 AK125643 AK298000 BAG60306 AK304337 BAG65182 AK307643 AL110106 BC005906 AAH05906 BC016714 BC020549 AAH20549 BC037425 AAH37425 BC064971 AAH64971 BC089385 AAH89385 BC110811 AAI10812 BC139731 AAI39732 BC151834 AAI51835 D29640 BAA06123 XM_005254984 XP_005255041 NM_003870 NP_003861
Function Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth. {ECO:0000269|PubMed:15695813}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15355962}.
Tissue Specificity Expressed in the placenta, lung, and kidney. A lower level expression is seen in the heart, liver, skeletal muscle and pancreas.
Top Pathways Adherens junction, Proteoglycans in cancer, Regulation of actin cytoskeleton

IQGAP1 CRISPR/Cas9 KO Plasmid (h) - sc-400597 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IQGAP1 HDR Plasmid (h) - sc-400597-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IQGAP1 Double Nickase Plasmid (h) - sc-400597-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IQGAP1 Double Nickase Plasmid (h2) - sc-400597-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IQGAP1 CRISPR Activation Plasmid (h) - sc-400597-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IQGAP1 CRISPR Activation Plasmid (h2) - sc-400597-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IQGAP1 Lentiviral Activation Particles (h) - sc-400597-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IQGAP1 Lentiviral Activation Particles (h2) - sc-400597-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IQGAP1 siRNA (h) - sc-35700 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IQGAP1 shRNA Plasmid (h) - sc-35700-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IQGAP1 shRNA (h) Lentiviral Particles - sc-35700-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IQGAP1 siRNA (h2) - sc-270066 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IQGAP1 shRNA Plasmid (h2) - sc-270066-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IQGAP1 shRNA (h2) Lentiviral Particles - sc-270066-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IQGAP1 RNAi - H00008826-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU137921 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10753 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11047 from Sigma-Aldrich

Category miRNA

IQGAP1 siRNA (Human) - CRH5824 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IQGAP1 - MBS8210358 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IQGAP1 (NM_003870.3) - SHH320409 from Creative biogene

Category siRNA
Species Reactivities Human

Human IQGAP1 siRNA - orb266326 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IQGAP1 shRNA Plasmid (Human) - CHH5824 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IQGAP1 miRNA 3'UTR clone - MiUTR1H-04982 from Creative biogene

Species Reactivities Human
Search more