Grin2b

Gene Symbol Grin2b
Entrez Gene 24410
Alt Symbol GluN2B
Species Rat
Gene Type protein-coding
Description glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Other Description N-methyl D-aspartate receptor subtype 2B|NMDAR2B|NR2B|glutamate [NMDA] receptor subunit epsilon-2|glutamate receptor ionotropic, NMDA 2B|glutamate receptor, ionotropic, NMDA2B
Swissprots Q00960 Q62684
Accessions EDM01617 EDM01618 Q00960 M91562 AAA41714 U11419 AAA50554 NM_012574 NP_036706
Function NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Top Pathways Rap1 signaling pathway, Circadian entrainment, Alcoholism, Cocaine addiction, cAMP signaling pathway

Anti-NMDAR2B (phospho Y1472) antibody - ab3856 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NMDAR2B Antibody - NB300-106 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NMDAR2B Antibody [NB300-106]

NMDAR2B [p Tyr1472] Antibody - NB300-182 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NMDAR2B Antibody (S59-20) - NBP1-47608 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S59-20
Western Blot: NMDAR2B Antibody (S59-20) [NBP1-47608] - analysis of Rat brain membrane lysate showing detection of GluN2B/NR2B protein using Mouse Anti-GluN2B/NR2B Monoclonal Antibody, Clone S59-20. Load: 15 ug protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-GluN2B/NR2B Monoclonal Antibody at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT.

NMDAR2B Antibody - NBP1-30037 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NMDAR2B Antibody [NBP1-30037]

NMDAR2B Antibody (S59-36) - NBP1-47611 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S59-36
Western Blot: NMDAR2B Antibody (S59-36) [NBP1-47611] - analysis of Rat brain membrane lysate showing detection of GluN2B/NR2B protein using Mouse Anti-GluN2B/NR2B Monoclonal Antibody, Clone S59-36. Load: 15 ug protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-GluN2B/NR2B Monoclonal Antibody at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT.

NMDAR2B [p Tyr1336] Antibody - NB300-295 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NMDAR2B [p Tyr1336] Antibody [NB300-295] - Analysis of Rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDAR (Control). The phosphospecificty of this labeling is shown in the second lane (lambda-phosphatase: lambda Ptase). The blot is identical to the control except that it was incubated in lambda Ptase (1200 units for 30 min) before being exposed to the Anti-Phospho-Tyr1336 NMDA NR2B subunit. The immunolabeling of NR2B is completely eliminated by treatment with lambda Ptase.

NMDAR2B Antibody - NB300-297 from Novus Biologicals

Prices $279.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NMDAR2B Antibody [NB300-297]

NMDAR2B [p Tyr1252] Antibody - NB300-292 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NMDAR2B [p Tyr1252] Antibody [NB300-292] - Rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit phosphorylated at Tyr1252 (Control). Phosphospecificity is shown in the second lane (lambda-phosphatase: lambda-Ptase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the phospho-Tyr1252 NMDA NR2B subunit antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase.

NMDAR2B [p Ser1166] Antibody - NBP2-29520 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NMDAR2B [p Ser1166] Antibody [NBP2-29520] - Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDAR phosphorylated at Ser1166 (Control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide), but not by the corresponding dephospho-peptide (not shown).

NMDAR2B [p Ser1480] Antibody - NB100-61103 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NMDAR2B [p Ser1480] Antibody [NB100-61103] - Rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDAR phosphorylated at Ser1480 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda-Ptase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the phospho-Ser1480 NMDA NR2B subunit antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase.

Anti-NMDANR2B antibody produced in rabbit - SAB4300711 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NMDANR2B: <B>Cat. No. SAB4300711</B>: Western blot analysis of extracts from T98G cells using Anti-NMDANR2B antibody.

NR2B/GluN2B Antibody (OASE00181) - OASE00181 from Aviva Systems Biology

Prices $350.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S59-20

NR2B Antibody (OASE00185) - OASE00185 from Aviva Systems Biology

Prices $350.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S59-36

NMDA-Receptor-NR2B-Subunit-Antibody - AN1232 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDA receptor.

Phospho-Ser1166-NMDA-Receptor-NR2B-Subunit-Antibody - AN1224 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDAR phosphorylated at Ser1166 (Control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide), but not by the corresponding dephospho-peptide (not shown).

Phospho-Ser1480-NMDA-Receptor-NR2B-Subunit-Antibody - AN1127 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDAR phosphorylated at Ser1480 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that it was incubated in λ-Ptase (1200 units for 30 min) before being exposed to the phospho-Ser1480 NMDA NR2B subunit antibody. The immunolabeling is completely eliminated by treatment with λ-Ptase.

NMDA-Receptor-NR2B-Subunit-Antibody - AN1091 from Abgent, a WuXi AppTec company

Prices $285.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western blot of 10 ug of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDA receptor.

NMDA-Receptor-NR2B-Subunit-Antibody - AN1056 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 10 µg
Host Rabbit
Clonality Polyclonal
Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDA receptor.

Phospho-Tyr1472-NMDA-NR2B-Subunit-Antibody - AN1019 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDAR phosphorylated at Tyr1472 (Control). The phosphospecificity is shown in the second lane where the immunolabeling is blocked by the phospho-peptide used as antigen (phos-pep) but not by the corresponding dephosphopeptide (not shown).

Phospho-Tyr1252-NMDA-Receptor-NR2B-Subunit-Antibody - AN1077 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit phosphorylated at Tyr1252 (Control). Phosphospecificity is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that it was incubated in λ-Ptase (1200 units for 30 min) before being exposed to the phospho-Tyr1252 NMDA NR2B subunit antibody. The immunolabeling is completely eliminated by treatment with λ-Ptase.

NMDA-Receptor-NR2B-Subunit-N-terminus-Antibody - AN1151 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of 10 ug of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDA receptor.

Phospho-Tyr1336-NMDA-Receptor-NR2B-Subunit-Antibody - AN1094 from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit phosphorylated at Tyr1336 (Control). Phosphospecificity is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that it was incubated in λ-Ptase (1200 units for 30 min) before being exposed to the phospho-Tyr1336 NMDA NR2B antibody. The immunolabeling is completely eliminated by treatment with λ-Ptase.

NMDA-Receptor-2B-NR2B-extracellular-Antibody - AG1265 from Abgent, a WuXi AppTec company

Prices $375.00, $475.00, $575.00
Sizes 25 µl, 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of rat brain lysates: 1. Anti-NMDA Receptor 2B (GluN2B) (extracellular) antibody (#AG1265), (1:600). 2. Anti-NMDA Receptor 2B (GluN2B) (extracellular) antibody, preincubated with the control peptide antigen.

NMDAR2B (phospho Tyr1472) antibody - GTX30452 from GeneTex

Prices $319.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Anti-NDMAR2B (phospho Tyr1472) antibody used in Western blot. GTX30452
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