NELFB

Gene Symbol NELFB
Entrez Gene 25920
Alt Symbol COBRA1, NELF-B
Species Human
Gene Type protein-coding
Description negative elongation factor complex member B
Other Description cofactor of BRCA1|negative elongation factor B|negative elongation factor protein B
Swissprots Q8WX92 Q96EW5 Q9Y3W0 Q9ULN8 Q9H9R4 A2BFA3
Accessions EAW88377 EAW88378 Q8WX92 AB033008 BAA86496 AF464935 AAL69965 AK022651 BAB14157 AK091056 BAG52272 AL050280 CAB43381 AM393289 CAL38167 BC011892 AAH11892 BC019029 DA210427 NM_015456 NP_056271
Function Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding. {ECO:0000269|PubMed:10199401, ECO:0000269|PubMed:12612062}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11739404}.
Tissue Specificity Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12612062}.

NELF-B CRISPR/Cas9 KO Plasmid (h) - sc-405667 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-B HDR Plasmid (h) - sc-405667-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-B Double Nickase Plasmid (h) - sc-405667-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-B Double Nickase Plasmid (h2) - sc-405667-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-B CRISPR Activation Plasmid (h) - sc-405667-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-B CRISPR Activation Plasmid (h2) - sc-405667-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-B Lentiviral Activation Particles (h) - sc-405667-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-B Lentiviral Activation Particles (h2) - sc-405667-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-B siRNA (h) - sc-75896 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELF-B shRNA Plasmid (h) - sc-75896-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELF-B shRNA (h) Lentiviral Particles - sc-75896-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

COBRA1 RNAi - H00025920-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU002641 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6356 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6356 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05782 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05782

NELFB siRNA (Human) - CRH8588 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

COBRA1 RNAi - H00025920-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human COBRA1 (NM_015456.3) - SHH266873 from Creative biogene

Category siRNA
Species Reactivities Human

Human NELFB siRNA - orb269090 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NELFB shRNA Plasmid (Human) - CHH8588 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

COBRA1 miRNA 3'UTR clone - MiUTR1H-02291 from Creative biogene

Species Reactivities Human
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