NELFB

Gene Symbol NELFB
Entrez Gene 25920
Alt Symbol COBRA1, NELF-B
Species Human
Gene Type protein-coding
Description negative elongation factor complex member B
Other Description cofactor of BRCA1|negative elongation factor B|negative elongation factor protein B
Swissprots Q8WX92 Q96EW5 Q9Y3W0 Q9ULN8 Q9H9R4 A2BFA3
Accessions EAW88377 EAW88378 Q8WX92 AB033008 BAA86496 AF464935 AAL69965 AK022651 BAB14157 AK091056 BAG52272 AL050280 CAB43381 AM393289 CAL38167 BC011892 AAH11892 BC019029 DA210427 NM_015456 NP_056271
Function Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding. {ECO:0000269|PubMed:10199401, ECO:0000269|PubMed:12612062}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11739404}.
Tissue Specificity Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12612062}.

COBRA1 (D6K9A) Rabbit mAb - 14894 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D6K9A
Western blot analysis of extracts from various cell lines using COBRA1 (D6K9A) Rabbit mAb.

NELF-B (C-19) - sc-79991 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NELF-B (G-18) - sc-79992 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NELF-B (H-300) - sc-366236 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NELF-B (H-300): sc-366236. Western blot analysis of NELF-B expression in human heart tissue extract.

Anti-COBRA1 antibody - ab92818 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Anti-COBRA1 antibody (ab92818) at 1/1000 dilution + neonatal Rat brain lysate

Anti-COBRA1 antibody - ab84984 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84984 at 1/250 dilution staining COBRA in human breast carcinoma by Immunofluorescence, Formalin-fixed, Paraffin-embedded tissue. Detection: Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte PlusTM 555 used at a dilution of 1/100.

Anti-COBRA1 antibody [EPR11200] - ab167401 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11200
ab167401 showing +ve staining in Human normal kidney.

Anti-NELFB / COBRA1 Antibody - LS-C211610 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (HRP) - LS-C211611 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (FITC) - LS-C211612 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (Biotin) - LS-C211613 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (aa255-285, AP) - LS-C255179 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (aa255-285, APC) - LS-C255180 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (aa255-285, Biotin) - LS-C255181 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (aa255-285, PE) - LS-C255183 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (aa255-285, FITC) - LS-C255182 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (clone F7E4) - LS-C150352 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone F7E4

Anti-NELFB / COBRA1 Antibody (aa25-75) - LS-C288680 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (clone 1A6-1C10) - LS-C307020 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A6-1C10

Anti-NELFB / COBRA1 Antibody (aa255-285) - LS-C329397 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NELFB / COBRA1 Antibody (aa256-285) - LS-C166908 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
COBRA1 Antibody western blot of 293 cell line lysates (35 ug/lane). The COBRA1 antibody detected the COBRA1 protein (arrow).

Anti-NELFB / COBRA1 Antibody (aa530-580) - LS-C288682 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human COBRA1 by Immunohistochemistry. Sample: FFPE section of human placenta. Antibody: Affinity purified rabbit anti-COBRA1 used at a dilution of 1:200 (1 ug/ml).

Anti-NELFB / COBRA1 Antibody (aa530-580) - LS-C286618 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human COBRA1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-COBRA1 used at a dilution of 1:250.

COBRA1 Antibody - NBP1-82924 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: COBRA1 Antibody [NBP1-82924] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

COBRA1 Antibody - NBP2-15935 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: COBRA1 Antibody [NBP2-15935] - Sample (30 ug of whole cell lysate) A: H1299 5% SDS PAGE gel, diluted at 1:1000.
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