| Gene Symbol |
BFAR
|
| Entrez Gene |
51283
|
| Alt Symbol |
BAR, RNF47
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
bifunctional apoptosis regulator
|
| Other Description |
RING finger protein 47|bifunctional apoptosis inhibitor
|
| Swissprots |
A8K4Z9 Q9NZS9 D3DUG8 B4DUT0
|
| Accessions |
EAW85105 EAW85106 EAW85107 EAW85108 EAW85109 Q9NZS9 AF173003 AAF59975 AK291114 BAF83803 AK297067 BAG59588 AK300778 BAG62442 AK313890 BAG36613 BC003054 AAH03054 BI912683 BU621058 DQ890648 ABM81574 DQ893828 ABM84754 XM_005255350 XP_005255407 XM_006725196 XP_006725259 XM_011522520 XP_011520822 XM_011546704 XP_011545006 NM_016561 NP_057645
|
| Function |
Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors. {ECO:0000269|PubMed:14502241}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}; Multi- pass membrane protein {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}.
|
| Tissue Specificity |
Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen. {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}.
|
![Western Blot: BFAR Overexpression Lysate (Adult Normal) [NBP2-04359] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BFAR.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/23214_BFAR%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-04359-img0001.jpg)