Gene Symbol | BFAR |
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Entrez Gene | 51283 |
Alt Symbol | BAR, RNF47 |
Species | Human |
Gene Type | protein-coding |
Description | bifunctional apoptosis regulator |
Other Description | RING finger protein 47|bifunctional apoptosis inhibitor |
Swissprots | A8K4Z9 Q9NZS9 D3DUG8 B4DUT0 |
Accessions | EAW85105 EAW85106 EAW85107 EAW85108 EAW85109 Q9NZS9 AF173003 AAF59975 AK291114 BAF83803 AK297067 BAG59588 AK300778 BAG62442 AK313890 BAG36613 BC003054 AAH03054 BI912683 BU621058 DQ890648 ABM81574 DQ893828 ABM84754 XM_005255350 XP_005255407 XM_006725196 XP_006725259 XM_011522520 XP_011520822 XM_011546704 XP_011545006 NM_016561 NP_057645 |
Function | Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors. {ECO:0000269|PubMed:14502241}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}; Multi- pass membrane protein {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}. |
Tissue Specificity | Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen. {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}. |
BAR CRISPR/Cas9 KO Plasmid (h) - sc-412170 from Santa Cruz Biotechnology
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BAR HDR Plasmid (h) - sc-412170-HDR from Santa Cruz Biotechnology
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BAR Double Nickase Plasmid (h) - sc-412170-NIC from Santa Cruz Biotechnology
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BAR Double Nickase Plasmid (h2) - sc-412170-NIC-2 from Santa Cruz Biotechnology
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BAR CRISPR Activation Plasmid (h) - sc-412170-ACT from Santa Cruz Biotechnology
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BAR CRISPR Activation Plasmid (h2) - sc-412170-ACT-2 from Santa Cruz Biotechnology
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BAR Lentiviral Activation Particles (h) - sc-412170-LAC from Santa Cruz Biotechnology
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BAR Lentiviral Activation Particles (h2) - sc-412170-LAC-2 from Santa Cruz Biotechnology
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BAR siRNA (h) - sc-37291 from Santa Cruz Biotechnology
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BAR shRNA Plasmid (h) - sc-37291-SH from Santa Cruz Biotechnology
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BAR shRNA (h) Lentiviral Particles - sc-37291-V from Santa Cruz Biotechnology
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BFAR RNAi - H00051283-R01V from Novus Biologicals
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MISSION® esiRNA - EHU018451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3959 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3959 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07910 from Sigma-Aldrich
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BFAR siRNA (Human) - CRH9661 from Cohesion Biosciences
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BFAR RNAi - H00051283-R01 from Novus Biologicals
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BFAR - MBS8235043 from MyBioSource
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shRNA set against Human BFAR (NM_016561.2) - SHH246482 from Creative biogene
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Human BFAR siRNA - orb270163 from Biorbyt
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BFAR shRNA Plasmid (Human) - CHH9661 from Cohesion Biosciences
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BFAR miRNA 3'UTR clone - MiUTR3H-13721 from Creative biogene
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