Gene Symbol |
BFAR
|
Entrez Gene |
51283
|
Alt Symbol |
BAR, RNF47
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
bifunctional apoptosis regulator
|
Other Description |
RING finger protein 47|bifunctional apoptosis inhibitor
|
Swissprots |
A8K4Z9 Q9NZS9 D3DUG8 B4DUT0
|
Accessions |
EAW85105 EAW85106 EAW85107 EAW85108 EAW85109 Q9NZS9 AF173003 AAF59975 AK291114 BAF83803 AK297067 BAG59588 AK300778 BAG62442 AK313890 BAG36613 BC003054 AAH03054 BI912683 BU621058 DQ890648 ABM81574 DQ893828 ABM84754 XM_005255350 XP_005255407 XM_006725196 XP_006725259 XM_011522520 XP_011520822 XM_011546704 XP_011545006 NM_016561 NP_057645
|
Function |
Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors. {ECO:0000269|PubMed:14502241}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}; Multi- pass membrane protein {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}.
|
Tissue Specificity |
Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen. {ECO:0000269|PubMed:10716992, ECO:0000269|PubMed:14502241}.
|